activity
20192025
most citedA joint model of unpaired data from scRNA-seq and spatial transcriptomics for imputing missing gene expression measurements

59 citations · 70 across the 10 of their papers we have counts for

collaborators

11 papers

cs.LG2025

Wrist Photoplethysmography Predicts Dietary Information

Kyle Verrier, Achille Nazaret, Joseph Futoma +2

Whether wearable photoplethysmography (PPG) contains dietary information remains unknown. We trained a language model on 1.1M meals to predict meal descriptions from PPG, aligning…

cs.CL2025

Model Directions, Not Words: Mechanistic Topic Models Using Sparse Autoencoders

Carolina Zheng, Nicolas Beltran-Velez, Sweta Karlekar +5

Traditional topic models are effective at uncovering latent themes in large text collections. However, due to their reliance on bag-of-words representations, they struggle to captu…

cs.LG2025

Extremely Greedy Equivalence Search

Achille Nazaret, David Blei

The goal of causal discovery is to learn a directed acyclic graph from data. One of the most well-known methods for this problem is Greedy Equivalence Search (GES). GES searches fo…

cs.AI2024

Hypothesis Testing the Circuit Hypothesis in LLMs

Claudia Shi, Nicolas Beltran-Velez, Achille Nazaret +5

Large language models (LLMs) demonstrate surprising capabilities, but we do not understand how they are implemented. One hypothesis suggests that these capabilities are primarily e…

cs.LG2024★ 1 cited

Treeffuser: Probabilistic Predictions via Conditional Diffusions with Gradient-Boosted Trees

Nicolas Beltran-Velez, Alessandro Antonio Grande, Achille Nazaret +2

Probabilistic prediction aims to compute predictive distributions rather than single point predictions. These distributions enable practitioners to quantify uncertainty, compute ri…

cs.LG2023★ 4 cited

Stable Differentiable Causal Discovery

Achille Nazaret, Justin Hong, Elham Azizi +1

Inferring causal relationships as directed acyclic graphs (DAGs) is an important but challenging problem. Differentiable Causal Discovery (DCD) is a promising approach to this prob…

cs.LG2023★ 5 cited

The CausalBench challenge: A machine learning contest for gene network inference from single-cell perturbation data

Mathieu Chevalley, Jacob Sackett-Sanders, Yusuf Roohani +15

In drug discovery, mapping interactions between genes within cellular systems is a crucial early step. Such maps are not only foundational for understanding the molecular mechanism…

stat.ME2023

On the Misspecification of Linear Assumptions in Synthetic Control

Achille Nazaret, Claudia Shi, David M. Blei

The synthetic control (SC) method is a popular approach for estimating treatment effects from observational panel data. It rests on a crucial assumption that we can write the treat…

cs.LG2022★ 1 cited

Variational Inference for Infinitely Deep Neural Networks

Achille Nazaret, David Blei

We introduce the unbounded depth neural network (UDN), an infinitely deep probabilistic model that adapts its complexity to the training data. The UDN contains an infinite sequence…

cs.LG2020

Stochastic Flows and Geometric Optimization on the Orthogonal Group

Krzysztof Choromanski, David Cheikhi, Jared Davis +12

We present a new class of stochastic, geometrically-driven optimization algorithms on the orthogonal group and naturally reductive homogeneous manifolds obtained from the ac…

cs.LG2019★ 59 cited

A joint model of unpaired data from scRNA-seq and spatial transcriptomics for imputing missing gene expression measurements

Romain Lopez, Achille Nazaret, Maxime Langevin +4

Spatial studies of transcriptome provide biologists with gene expression maps of heterogeneous and complex tissues. However, most experimental protocols for spatial transcriptomics…