3 papers
q-bio.PE2020
A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection
Claus Vogl, Lynette Caitlin Mikula
In this article, a biallelic reversible mutation model with linear and quadratic selection is analyzed. The approach reconnects to one proposed by Kimura ( Possibility of extensive…
q-bio.PE2019
Maximum likelihood estimators for scaled mutation rates in an equilibrium mutation-drift model
Claus Vogl, Lynette C. Mikula, Conrad J. Burden
The stationary sampling distribution of a neutral decoupled Moran or Wright-Fisher diffusion with neutral mutations is known to first order for a general rate matrix with small but…
q-bio.PE2019
Maximum likelihood (ML) estimators for scaled mutation parameters with a strand symmetric mutation model in equilibrium
Claus Vogl, Lynette Caitlin Mikula
With the multiallelic parent-independent mutation-drift model, the equilibrium proportions of alleles are known to be Dirichlet distributed. A special case is the biallelic model,…