12 citations · 18 across the 7 of their papers we have counts for
7 papers
A joint QoL-Survival framework with debiased estimation under truncation by death
Torben Martinussen, Klaus K. Holst, Christian Bressen Pipper +1
Evaluating quality-of-life (QoL) outcomes in populations with high mortality risk is complicated by truncation by death, since QoL is undefined for individuals who do not survive t…
Estimation methods for estimands using the treatment policy strategy; a simulation study based on the PIONEER 1 Trial
James Bell, Thomas Drury, Tobias Mütze +6
Estimands using the treatment policy strategy for addressing intercurrent events are common in Phase III clinical trials. One estimation approach for this strategy is retrieved dro…
Unbiased and Efficient Estimation of Causal Treatment Effects in Cross-over Trials
Jeppe Ekstrand Halkjær Madsen, Thomas Scheike, Christian Pipper
We introduce causal inference reasoning to cross-over trials, with a focus on Thorough QT (TQT) studies. For such trials, we propose different sets of assumptions and consider thei…
Properties of a confirmatory two-stage adaptive procedure for assessing average bioequivalence
Marie Louise Østerdal, Kyle Raymond, Christian Pipper
We investigate a confirmatory two stage adaptive procedure for assessing average bioequivalence and provide some insights to its theoretical properties. Effectively, we perform Two…
A hypothesis testing framework for the ratio of means of two negative binomial distributions: classifying the efficacy of anthelmintic treatment against intestinal parasites
Matthew Denwood, Giles Innocent, Jamie Prentice +9
Over-dispersed count data typically pose a challenge to analysis using standard statistical methods, particularly when evaluating the efficacy of an intervention through the observ…
Moment-based Estimation of Mixtures of Regression Models
Claus Thorn Ekstrøm, Christian Bressen Pipper
Finite mixtures of regression models provide a flexible modeling framework for many phenomena. Using moment-based estimation of the regression parameters, we develop unbiased estim…