90 citations · 236 across the 9 of their papers we have counts for
9 papers
Nonlinear Biochemical Signal Processing via Noise Propagation
Kyung Hyuk Kim, Hong Qian, Herbert M. Sauro
Single-cell studies often show significant phenotypic variability due to the stochastic nature of intra-cellular biochemical reactions. When the numbers of molecules, e.g., transcr…
Fan-out in Gene Regulatory Networks
Kyung Hyuk Kim, Herbert M. Sauro
In synthetic biology, gene regulatory circuits are often constructed by combining smaller circuit components. Connections between components are achieved by transcription factors a…
Measuring the Degree of Modularity from Gene Expression Noise in Gene Regulatory Circuits
Kyung Hyuk Kim, Herbert M. Sauro
Gene regulatory circuits show significant stochastic fluctuations in their circuit signals due to the low copy number of transcription factors. When a gene circuit component is con…
Stochastic Control Analysis for Biochemical Reaction Systems
Kyung Hyuk Kim, Herbert M. Sauro
In this paper, we investigate how stochastic reaction processes are affected by external perturbations. We describe an extension of the deterministic metabolic control analysis (MC…
Sensitivity Regulation based on Noise Propagation in Stochastic Reaction Networks
Kyung Hyuk Kim, Hong Qian, Herbert M. Sauro
In this work we focus on how noise propagates in biochemical reaction networks and affects sensitivities of the system. We discover that the stochastic fluctuations can enhance sen…
Dynamic Screening in a Two-Species Asymmetric Exclusion Process
Kyung Hyuk Kim, Marcel den Nijs
The dynamic scaling properties of the one dimensional Burgers equation are expected to change with the inclusion of additional conserved degrees of freedom. We study this by means…