activity
20102019
most citedToolbox model of evolution of prokaryotic metabolic networks and their regulation

125 citations · 219 across the 5 of their papers we have counts for

collaborators

8 papers

q-bio.PE2019

On age-specific selection and extensive lifespan beyond menopause

Tin Yau Pang

Extensive post reproductive lifespan (PRLS) is observed only in a few species, such as humans or resident killer whales, and its origin is under debate. Hypotheses like mother-care…

q-bio.GN2016

Supra-operonic clusters of functionally related genes (SOCs) are a source of horizontal gene co-transfers

Tin Y Pang, Martin Lercher

Adaptation of bacteria occurs predominantly via horizontal gene transfer (HGT). While it is widely recognized that horizontal acquisitions frequently encompass multiple genes, it i…

q-bio.PE2015

The adaptive acquisition of single DNA segments drives metabolic evolution across E. coli lineages

Tin Y. Pang, Martin Lercher

Even closely related prokaryotes show an astounding diversity in their ability to grow in different nutritional environments. Mechanistically, this diversity arises predominantly t…

q-bio.GN2015★ 93 cited

Recombinant transfer in the basic genome of E. coli

Purushottam Dixit, Tin Yau Pang, F. William Studier +1

An approximation to the ~4 Mbp basic genome shared by 32 strains of E. coli representing six evolutionary groups has been derived and analyzed computationally. A multiple-alignment…

q-bio.PE2014★ 1 cited

Quantifying evolutionary dynamics of the basic genome of E. coli

Purushottam Dixit, Tin Yau Pang, F. William Studier +1

The ~4-Mbp basic genome shared by 32 independent isolates of E. coli representing considerable population diversity has been approximated by whole-genome multiple-alignment and com…

q-bio.MN2013

Universal distribution of component frequencies in biological and technological systems

Tin Yau Pang, Sergei Maslov

Bacterial genomes and large-scale computer software projects both consist of a large number of components (genes or software packages) connected via a network of mutual dependencie…