28 citations · 28 across the 5 of their papers we have counts for
12 papers
Interplay between Contractivity and Monotonicity for Reaction Networks
Alon Duvall, M. Ali Al-Radhawi, Dhruv D. Jatkar +1
We establish a new relationship between monotonicity and contractivity and use this connection to describe a new general class of weakly contractive reaction networks. The new clas…
Competition for binding targets results in paradoxical effects for simultaneous activator and repressor action -- Extended Version
M. Ali Al-Radhawi, Krishna Manoj, Dhruv D. Jatkar +3
In the context of epigenetic transformations in cancer metastasis, a puzzling effect was recently discovered, in which the elimination (knock-out) of an activating regulatory eleme…
On structural contraction of biological interaction networks
M. Ali Al-Radhawi, David Angeli, Eduardo Sontag
Biological networks are customarily described as structurally robust. This means that they often function extremely well under large forms of perturbations affecting both the conce…
Graphical characterizations of robust stability in biological interaction networks
M. Ali Al-Radhawi
Previous studies have inferred robust stability of reaction networks by utilizing linear programs or iterative algorithms. Such algorithms become tedious or computationally infeasi…
Epigenetic factor competition reshapes the EMT landscape
M. Ali Al-Radhawi, Shubham Tripathi, Yun Zhang +2
The emergence of and transitions between distinct phenotypes in isogenic cells can be attributed to the intricate interplay of epigenetic marks, external signals, and gene regulato…
Long-term regulation of prolonged epidemic outbreaks in large populations via adaptive control: a singular perturbation approach
M. Ali Al-Radhawi, Mahdiar Sadeghi, Eduardo D. Sontag
Initial hopes of quickly eradicating the COVID-19 pandemic proved futile, and the goal shifted to controlling the peak of the infection, so as to minimize the load on healthcare sy…