233 citations · 821 across the 23 of their papers we have counts for
5 papers · 1 filter
A Unified View of Relational Deep Learning for Drug Pair Scoring
Benedek Rozemberczki, Stephen Bonner, Andriy Nikolov +3
In recent years, numerous machine learning models which attempt to solve polypharmacy side effect identification, drug-drug interaction prediction and combination therapy design ta…
Implications of Topological Imbalance for Representation Learning on Biomedical Knowledge Graphs
Stephen Bonner, Ufuk Kirik, Ola Engkvist +2
Adoption of recently developed methods from machine learning has given rise to creation of drug-discovery knowledge graphs (KG) that utilize the interconnected nature of the domain…
A Knowledge Graph-Enhanced Tensor Factorisation Model for Discovering Drug Targets
Cheng Ye, Rowan Swiers, Stephen Bonner +1
The drug discovery and development process is a long and expensive one, costing over 1 billion USD on average per drug and taking 10-15 years. To reduce the high levels of attritio…
Understanding the Performance of Knowledge Graph Embeddings in Drug Discovery
Stephen Bonner, Ian P Barrett, Cheng Ye +4
Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in…
A Review of Biomedical Datasets Relating to Drug Discovery: A Knowledge Graph Perspective
Stephen Bonner, Ian P Barrett, Cheng Ye +5
Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of…