37 citations · 101 across the 6 of their papers we have counts for
4 papers · 1 filter
Deformability and collision-induced reorientation enhance cell topotaxis in dense microenvironments
Leonie van Steijn, Joeri A. J. Wondergem, Koen Schakenraad +2
In vivo, cells navigate through complex environments filled with obstacles. Recently, the term 'topotaxis' has been introduced for navigation along topographic cues such as obstacl…
Mechanical interplay between cell shape and actin cytoskeleton organization
Koen Schakenraad, Jeremy Ernst, Wim Pomp +4
We investigate the mechanical interplay between the spatial organization of the actin cytoskeleton and the shape of animal cells adhering on micropillar arrays. Using a combination…
Cytoskeletal Anisotropy Controls Geometry and Forces of Adherent Cells
Wim Pomp, Koen Schakenraad, Hayri E. Balcioğlu +5
We investigate the geometrical and mechanical properties of adherent cells characterized by a highly anisotropic actin cytoskeleton. Using a combination of theoretical work and exp…
Modeling the effect of intercalators on the high-force stretching behavior of DNA
Koen Schakenraad, Iddo Heller, Andreas Biebricher +3
DNA is structurally and mechanically altered by the binding of intercalator molecules. Intercalation strongly affects the force-extension behavior of DNA, in particular the overstr…