activity
20192022
most citedChemRL-GEM: Geometry Enhanced Molecular Representation Learning for Property Prediction

616 citations · 931 across the 24 of their papers we have counts for

collaborators

25 papers

cs.CL2022

Query Enhanced Knowledge-Intensive Conversation via Unsupervised Joint Modeling

Mingzhu Cai, Siqi Bao, Xin Tian +3

In this paper, we propose an unsupervised query enhanced approach for knowledge-intensive conversations, namely QKConv. There are three modules in QKConv: a query generator, an off…

cs.CL2022★ 3 cited

PLATO-K: Internal and External Knowledge Enhanced Dialogue Generation

Siqi Bao, Huang He, Jun Xu +7

Recently, the practical deployment of open-domain dialogue systems has been plagued by the knowledge issue of information deficiency and factual inaccuracy. To this end, we introdu…

cs.CL2022★ 1 cited

Q-TOD: A Query-driven Task-oriented Dialogue System

Xin Tian, Yingzhan Lin, Mengfei Song +5

Existing pipelined task-oriented dialogue systems usually have difficulties adapting to unseen domains, whereas end-to-end systems are plagued by large-scale knowledge bases in pra…

cs.CL2022

Towards Boosting the Open-Domain Chatbot with Human Feedback

Hua Lu, Siqi Bao, Huang He +3

Many open-domain dialogue models pre-trained with social media comments can generate coherent replies but have difficulties producing engaging responses when interacting with real…

cs.LG2022★ 3 cited

GEM-2: Next Generation Molecular Property Prediction Network by Modeling Full-range Many-body Interactions

Lihang Liu, Donglong He, Xiaomin Fang +4

Molecular property prediction is a fundamental task in the drug and material industries. Physically, the properties of a molecule are determined by its own electronic structure, wh…

cs.DC2022★ 30 cited

HelixFold: An Efficient Implementation of AlphaFold2 using PaddlePaddle

Guoxia Wang, Xiaomin Fang, Zhihua Wu +6

Accurate protein structure prediction can significantly accelerate the development of life science. The accuracy of AlphaFold2, a frontier end-to-end structure prediction system, i…

q-bio.BM2022★ 104 cited

HelixFold-Single: MSA-free Protein Structure Prediction by Using Protein Language Model as an Alternative

Xiaomin Fang, Fan Wang, Lihang Liu +7

AI-based protein structure prediction pipelines, such as AlphaFold2, have achieved near-experimental accuracy. These advanced pipelines mainly rely on Multiple Sequence Alignments…

cs.CL2022★ 5 cited

Link the World: Improving Open-domain Conversation with Dynamic Spatiotemporal-aware Knowledge

Han Zhou, Xinchao Xu, Wenquan Wu +5

Making chatbots world aware in a conversation like a human is a crucial challenge, where the world may contain dynamic knowledge and spatiotemporal state. Several recent advances h…

q-bio.BM2022★ 62 cited

HelixADMET: a robust and endpoint extensible ADMET system incorporating self-supervised knowledge transfer

Shanzhuo Zhang, Zhiyuan Yan, Yueyang Huang +8

Accurate ADMET (an abbreviation for "absorption, distribution, metabolism, excretion, and toxicity") predictions can efficiently screen out undesirable drug candidates in the early…

cs.CL2021★ 3 cited

TOD-DA: Towards Boosting the Robustness of Task-oriented Dialogue Modeling on Spoken Conversations

Xin Tian, Xinxian Huang, Dongfeng He +11

Task-oriented dialogue systems have been plagued by the difficulties of obtaining large-scale and high-quality annotated conversations. Furthermore, most of the publicly available…

cs.LG2021

Docking-based Virtual Screening with Multi-Task Learning

Zijing Liu, Xianbin Ye, Xiaomin Fang +3

Machine learning shows great potential in virtual screening for drug discovery. Current efforts on accelerating docking-based virtual screening do not consider using existing data…

q-bio.BM2021★ 4 cited

Multimodal Pre-Training Model for Sequence-based Prediction of Protein-Protein Interaction

Yang Xue, Zijing Liu, Xiaomin Fang +1

Protein-protein interactions (PPIs) are essentials for many biological processes where two or more proteins physically bind together to achieve their functions. Modeling PPIs is us…

cs.LG2021★ 6 cited

HelixMO: Sample-Efficient Molecular Optimization in Scene-Sensitive Latent Space

Zhiyuan Chen, Xiaomin Fang, Zixu Hua +3

Efficient exploration of the chemical space to search the candidate drugs that satisfy various constraints is a fundamental task of drug discovery. Advanced deep generative methods…

cs.CL2021

Amendable Generation for Dialogue State Tracking

Xin Tian, Liankai Huang, Yingzhan Lin +6

In task-oriented dialogue systems, recent dialogue state tracking methods tend to perform one-pass generation of the dialogue state based on the previous dialogue state. The mistak…

cs.CL2021★ 17 cited

PLATO-XL: Exploring the Large-scale Pre-training of Dialogue Generation

Siqi Bao, Huang He, Fan Wang +11

To explore the limit of dialogue generation pre-training, we present the models of PLATO-XL with up to 11 billion parameters, trained on both Chinese and English social media conve…

cs.AI2021

Evolving Decomposed Plasticity Rules for Information-Bottlenecked Meta-Learning

Fan Wang, Hao Tian, Haoyi Xiong +5

Artificial neural networks (ANNs) are typically confined to accomplishing pre-defined tasks by learning a set of static parameters. In contrast, biological neural networks (BNNs) c…

cs.LG2021★ 616 cited

ChemRL-GEM: Geometry Enhanced Molecular Representation Learning for Property Prediction

Xiaomin Fang, Lihang Liu, Jieqiong Lei +6

Effective molecular representation learning is of great importance to facilitate molecular property prediction, which is a fundamental task for the drug and material industry. Rece…

cs.CL2021★ 5 cited

A Unified Pre-training Framework for Conversational AI

Siqi Bao, Bingjin Chen, Huang He +7

In this work, we explore the application of PLATO-2 on various dialogue systems, including open-domain conversation, knowledge grounded dialogue, and task-oriented conversation. PL…

cs.CL2021

Learning to Select External Knowledge with Multi-Scale Negative Sampling

Huang He, Hua Lu, Siqi Bao +4

The Track-1 of DSTC9 aims to effectively answer user requests or questions during task-oriented dialogues, which are out of the scope of APIs/DB. By leveraging external knowledge r…

cs.RO2020

Proactive Interaction Framework for Intelligent Social Receptionist Robots

Yang Xue, Fan Wang, Hao Tian +4

Proactive human-robot interaction (HRI) allows the receptionist robots to actively greet people and offer services based on vision, which has been found to improve acceptability an…

cs.CL2020★ 27 cited

PLATO-2: Towards Building an Open-Domain Chatbot via Curriculum Learning

Siqi Bao, Huang He, Fan Wang +6

To build a high-quality open-domain chatbot, we introduce the effective training process of PLATO-2 via curriculum learning. There are two stages involved in the learning process.…

cs.CL2019★ 15 cited

PLATO: Pre-trained Dialogue Generation Model with Discrete Latent Variable

Siqi Bao, Huang He, Fan Wang +2

Pre-training models have been proved effective for a wide range of natural language processing tasks. Inspired by this, we propose a novel dialogue generation pre-training framewor…

cs.CL2019★ 6 cited

Generating Multiple Diverse Responses with Multi-Mapping and Posterior Mapping Selection

Chaotao Chen, Jinhua Peng, Fan Wang +2

In human conversation an input post is open to multiple potential responses, which is typically regarded as a one-to-many problem. Promising approaches mainly incorporate multiple…

cs.CL2019★ 1 cited

Know More about Each Other: Evolving Dialogue Strategy via Compound Assessment

Siqi Bao, Huang He, Fan Wang +2

In this paper, a novel Generation-Evaluation framework is developed for multi-turn conversations with the objective of letting both participants know more about each other. For the…