191 citations · 284 across the 23 of their papers we have counts for
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The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth
Erik van Dijk, Juami Hermine Mariama van Gils, Alessia Peduzzo +6
Many proteins have the potential to aggregate into amyloid fibrils, which are associated with a wide range of human disorders including Alzheimer's and Parkinson's disease. In cont…
Consistent treatment of hydrophobicity in protein lattice models accounts for cold denaturation
Erik van Dijk, Patrick Varilly, Tuomas Knowles +2
The hydrophobic effect stabilizes the native structure of proteins by minimizing the unfavourable interactions between hydrophobic residues and water through the formation of a hyd…
The competition between surface adsorption and folding of fibril-forming polypeptides
Ran Ni, J. Mieke Kleijn, Sanne Abeln +2
Self-assembly of polypeptides into fibrillar structures can be initiated by planar surfaces that interact favorably with certain residues. Using a coarse grained model, we systemat…
Interplay between folding and assembly of fibril-forming polypeptides
Ran Ni, Sanne Abeln, Marieke Schor +2
Polypeptides can self-assemble into hierarchically organized fibrils consisting of a stack of individually folded polypeptides driven together by hydrophobic interaction. Using a c…