45 citations · 134 across the 11 of their papers we have counts for
4 papers · 1 filter
Kinetic limitations of cooperativity based drug delivery systems
Nicholas A. Licata, Alexei V. Tkachenko
We study theoretically a novel drug delivery system that utilizes the overexpression of certain proteins in cancerous cells for cell specific chemotherapy. The system consists of d…
Elasticity of strongly stretched ssDNA
Alexei V. Tkachenko
We present a simple model which describes elastic response of single-stranded DNA (ssDNA) to stretching, including the regime of very high force (up to 1000 pN). ssDNA is modelled…
Role of boundary constraints in DNA cyclization
Alexei V. Tkachenko
We modify the classical Shimada-Yamakawa theory of DNA looping by generalizing the form of boundary constraints. This generalization is important in the context of DNA cyclization…
Colloids with key-lock interactions: non-exponential relaxation, aging and anomalous diffusion
Nicholas A. Licata, Alexei V. Tkachenko
The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Experimental realizations of such systems include colloids grafted wit…