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Identifying topologically associating domains using differential kernels
Luka Maisuradze, Megan C. King, Ivan V. Surovtsev +3
Chromatin is a polymer complex of DNA and proteins that regulates gene expression. The three-dimensional structure and organization of chromatin controls DNA transcription and repl…
Modeling the effects of varying Ti concentration on the mechanical properties of Cu-Ti alloys
Vasileios Fotopoulos, Corey S. O'Hern, Mark D. Shattuck +1
The mechanical properties of Cu-Ti alloys have been characterized extensively through experimental studies. However, a detailed understanding of why the strength of Cu increases af…
The connection between polymer collapse and the onset of jamming
Alex T. Grigas, Aliza Fisher, Mark D. Shattuck +1
Previous studies have shown that the interiors of proteins are densely packed, reaching packing fractions that are as large as those found for static packings of individual amino-a…
Universal Mechanical Polycomputation in Granular Matter
Atoosa Parsa, Sven Witthaus, Nidhi Pashine +3
Unconventional computing devices are increasingly of interest as they can operate in environments hostile to silicon-based electronics, or compute in ways that traditional electron…
Mechanical Plasticity of Cell Membranes Enhances Epithelial Wound Closure
Andrew T. Ton, Arthur K. MacKeith, Mark D. Shattuck +1
During epithelial wound healing, cell morphology near the healed wound and the healing rate vary strongly among different developmental stages even for a single species like \texti…
Tessellated granular metamaterials with tunable elastic moduli
Nidhi Pashine, Dong Wang, Jerry Zhang +5
Most granular packings possess shear moduli () that increase with the applied external pressure, and bulk moduli () that increase or remain constant with pressure. This paper…