activity
20182023
most citedConFiG: Contextual Fibre Growth to generate realistic axonal packing for diffusion MRI simulation

44 citations · 83 across the 9 of their papers we have counts for

collaborators

9 papers

physics.med-ph2023★ 1 cited

Machine-learning-informed parameter estimation improves the reliability of spinal cord diffusion MRI

Ting Gong, Francesco Grussu, Claudia A. M. Gandini Wheeler-Kingshott +2

Purpose: We address the challenge of inaccurate parameter estimation in diffusion MRI when the signal-to-noise ratio (SNR) is very low, as in the spinal cord. The accuracy of conve…

q-bio.QM2021★ 7 cited

MAGORINO: Magnitude-only fat fraction and R2* estimation with Rician noise modelling

Timothy JP Bray, Alan Bainbridge, Margaret A Hall-Craggs +1

Purpose: Magnitude-based fitting of chemical shift-encoded data enables proton density fat fraction (PDFF) and R2* estimation where complex-based methods fail or when phase data is…

physics.med-ph2021★ 4 cited

Task-driven assessment of experimental designs in diffusion MRI: a computational framework

Sean C. Epstein, Timothy J. P. Bray, Margaret A. Hall-Craggs +1

This paper proposes a task-driven computational framework for assessing diffusion MRI experimental designs which, rather than relying on parameter-estimation metrics, directly meas…

physics.med-ph2021

Impact of within-voxel heterogeneity in fibre geometry on spherical deconvolution

Ross Callaghan, Daniel C. Alexander, Marco Palombo +1

Axons in white matter have been shown to have varying geometries within a bundle using ex vivo imaging techniques, but what does this mean for diffusion MRI (dMRI) based spherical…

physics.med-ph2020

Mapping complex cell morphology in the grey matter with double diffusion encoding MR: a simulation study

Andrada Ianus, Daniel C. Alexander, Hui Zhang +1

This paper investigates the impact of cell body (soma) size and branching of cellular projections on diffusion MR imaging (dMRI) and spectroscopy (dMRS) signals for both standard s…

physics.med-ph2020★ 44 cited

ConFiG: Contextual Fibre Growth to generate realistic axonal packing for diffusion MRI simulation

Ross Callaghan, Daniel C. Alexander, Marco Palombo +1

This paper presents Contextual Fibre Growth (ConFiG), an approach to generate white matter numerical phantoms by mimicking natural fibre genesis. ConFiG grows fibres one-by-one, fo…

physics.med-ph2019

Machine learning based white matter models with permeability: An experimental study in cuprizone treated in-vivo mouse model of axonal demyelination

Ioana Hill, Marco Palombo, Mathieu Santin +14

The intra-axonal water exchange time τi, a parameter associated with axonal permeability, could be an important biomarker for understanding demyelinating pathologies such as Multip…

physics.med-ph2019★ 26 cited

SANDI: a compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

Marco Palombo, Andrada Ianus, Daniel Nunes +4

This work introduces a compartment-based model for apparent soma and neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The existing conjecture in…

physics.med-ph2018★ 1 cited

A generative model of realistic brain cells with application to numerical simulation of diffusion-weighted MR signal

Marco Palombo, Daniel C. Alexander, Hui Zhang

In this work, we introduce a novel computational framework that we developed to use numerical simulations to investigate the complexity of brain tissue at a microscopic level with…