87 citations · 212 across the 6 of their papers we have counts for
6 papers
Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions
Meng Liu, Azzurra Apriceno, Miguel Sipin +6
From viruses to nanoparticles, constructs functionalized with multiple ligands display peculiar binding properties that only arise from multivalent effects. Using statistical mecha…
4D Liquid-phase Electron Microscopy of Ferritin by Brownian Single Particle Analysis
Gabriele Marchello, Cesare De Pace, Neil Wilkinson +2
Protein function and activity are a consequence of its three-dimensional structure. Single particle analysis of cryogenic electron micrographs has radically changed structural biol…
Protein structure, activity and thermal stability within nanoscopic compartments
Denis Cecchin Luca Chierico, Xiaohe Tian, Katharina Kluthe +4
We report that protein confinement within nanoscopic vesicular compartments corresponds to a liquid-liquid phase transition with the protein/water within vesicle lumen interacting…
Polymersomes confined self-assembly: micellisation in 2D
Lorena Ruiz-Perez, Lea Messager, Jens Gaitzsch +4
Biological systems exploit self-assembly to create complex structures whose arrangements are finely controlled from molecular to mesoscopic level. Herein we report an example of us…
Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord
Michela Fratini, Inna Bukreeva, Gaetano Campi +11
Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking kno…
Effect of interactions on the cellular uptake of nanoparticles
Abhishek Chaudhuri, Giuseppe Battaglia, Ramin Golestanian
We present a simple two-state model to understand the size-dependent endocytosis of nanoparticles. Using this model, we elucidate the relevant energy terms required to understand t…