16 citations · 58 across the 18 of their papers we have counts for
8 papers · 1 filter
TopoCellGen: Generating Histopathology Cell Topology with a Diffusion Model
Meilong Xu, Saumya Gupta, Xiaoling Hu +5
Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides critical insights into tissue structure and pathology. The synthetic generation of cel…
RankByGene: Gene-Guided Histopathology Representation Learning Through Cross-Modal Ranking Consistency
Wentao Huang, Meilong Xu, Xiaoling Hu +9
Spatial transcriptomics (ST) provides essential spatial context by mapping gene expression within tissue, enabling detailed study of cellular heterogeneity and tissue organization.…
Semi-Supervised Contrastive VAE for Disentanglement of Digital Pathology Images
Mahmudul Hasan, Xiaoling Hu, Shahira Abousamra +3
Despite the strong prediction power of deep learning models, their interpretability remains an important concern. Disentanglement models increase interpretability by decomposing th…
Semi-supervised Segmentation of Histopathology Images with Noise-Aware Topological Consistency
Meilong Xu, Xiaoling Hu, Saumya Gupta +2
In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consumin…
Topology-Guided Multi-Class Cell Context Generation for Digital Pathology
Shahira Abousamra, Rajarsi Gupta, Tahsin Kurc +3
In digital pathology, the spatial context of cells is important for cell classification, cancer diagnosis and prognosis. To model such complex cell context, however, is challenging…
Federated Learning for the Classification of Tumor Infiltrating Lymphocytes
Ujjwal Baid, Sarthak Pati, Tahsin M. Kurc +6
We evaluate the performance of federated learning (FL) in developing deep learning models for analysis of digitized tissue sections. A classification application was considered as…
Learning from Thresholds: Fully Automated Classification of Tumor Infiltrating Lymphocytes for Multiple Cancer Types
Shahira Abousamra, Le Hou, Rajarsi Gupta +7
Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types…
Utilizing Automated Breast Cancer Detection to Identify Spatial Distributions of Tumor Infiltrating Lymphocytes in Invasive Breast Cancer
Han Le, Rajarsi Gupta, Le Hou +12
Quantitative assessment of Tumor-TIL spatial relationships is increasingly important in both basic science and clinical aspects of breast cancer research. We have developed and eva…