8 papers
Achieving detailed medial temporal lobe segmentation with upsampled isotropic training from implicit neural representation
Yue Li, Pulkit Khandelwal, Rohit Jena +8
Imaging biomarkers in magnetic resonance imaging (MRI) are important tools for diagnosing, tracking and treating Alzheimer's disease (AD). Neurofibrillary tau pathology in AD is cl…
Imaging Biomarkers for Neurodegenerative Diseases from Detailed Segmentation of Medial Temporal Lobe Subregions on in vivo Brain MRI Using Upsampling Strategy Guided by High-resolution ex vivo MRI
Yue Li, Pulkit Khandelwal, Long Xie +21
The medial temporal lobe (MTL) is a region impacted extensively and non-uniformly in early stages of Alzheimer's disease (AD). Regional MTL morphometric measures extracted from mag…
Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRI
Mengjin Dong, Long Xie, Sandhitsu R. Das +5
Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer's disease (AD). In clinical…
Improved Segmentation of Deep Sulci in Cortical Gray Matter Using a Deep Learning Framework Incorporating Laplace's Equation
Sadhana Ravikumar, Ranjit Ittyerah, Sydney Lim +29
When developing tools for automated cortical segmentation, the ability to produce topologically correct segmentations is important in order to compute geometrically valid morphomet…
Deep Label Fusion: A 3D End-to-End Hybrid Multi-Atlas Segmentation and Deep Learning Pipeline
Long Xie, Laura E. M. Wisse, Jiancong Wang +6
Deep learning (DL) is the state-of-the-art methodology in various medical image segmentation tasks. However, it requires relatively large amounts of manually labeled training data,…
DeepAtrophy: Teaching a Neural Network to Differentiate Progressive Changes from Noise on Longitudinal MRI in Alzheimer's Disease
Mengjin Dong, Long Xie, Sandhitsu R. Das +5
Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clin…
Barnes-Hut Approximation for Point SetGeodesic Shooting
Jiancong Wang, Long Xie, Paul Yushkevich +1
Geodesic shooting has been successfully applied to diffeo-morphic registration of point sets. Exact computation of the geodesicshooting between point sets, however, requiresO(N2) c…
Diffeomorphic Medial Modeling
Paul A. Yushkevich, Ahmed Aly, Jiancong Wang +4
Deformable shape modeling approaches that describe objects in terms of their medial axis geometry (e.g., m-reps [Pizer et al., 2003]) yield rich geometrical features that can be us…