5 papers
PDMS microfluidic film for in vitro engineering of mesoscale neuronal networks
Taiki Takemuro, Hideaki Yamamoto, Shigeo Sato +1
Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes wh…
Characterization of bulk nanobubbles formed by using a porous alumina film with ordered nanopores
Teng Ma, Yasuo Kimura, Hideaki Yamamoto +3
Gaseous nanobubbles (NBs), with their unique physicochemical properties and promising applications, have become an important research topic. Generation of monodispersed bulk NBs wi…
Optical transport of sub-micron lipid vesicles along an optical nanofibre
Takaaki Yoshino, Daichi Yamaura, Maki Komiya +6
Enhanced manipulation and analysis of bio-particles using light confined in nano-scale dielectric structures has proceeded apace in the last several years. Small mode volumes, alon…
Suppression of hypersynchronous network activity in cultured cortical neurons using an ultrasoft silicone scaffold
Takuma Sumi, Hideaki Yamamoto, Ayumi Hirano-Iwata
The spontaneous activity pattern of cortical neurons in dissociated culture is characterized by burst firing that is highly synchronized among a wide population of cells. The degre…
A Teflon-based system for applying multidirectional voltages to lipid bilayers as a novel platform for membrane proteins
Maki Komiya, Kensaku Kanomata, Ryo Yokota +13
Artificial bilayer lipid membranes (BLMs), along with patch-clamped membranes, are frequently used for functional analyses of membrane proteins. In both methods, the electric prope…