69 citations · 220 across the 12 of their papers we have counts for
12 papers
Genesis of a Horizontal Electric Field within the Lipid Bilayer: A Bilayer-Embedded Actuation Platform
Maki Komiya, Madoka Sato, Teng Ma +19
The electric field of biological membranes has long been treated as a one-dimensional quantity, defined solely by the component normal to the bilayer (E_VERT). Here, we present a b…
Precision microfluidic control of neuronal ensembles in cultured cortical networks
Hakuba Murota, Hideaki Yamamoto, Nobuaki Monma +2
In vitro neuronal culture is an important research platform in cellular and network neuroscience. However, neurons cultured on a homogeneous scaffold form dense, randomly connected…
Directional intermodular coupling enriches functional complexity in biological neuronal networks
Nobuaki Monma, Hideaki Yamamoto, Naoya Fujiwara +4
Hierarchically modular organization is a canonical network topology that is evolutionarily conserved in the nervous systems of animals. Within the network, neurons form directional…
Model-Free Idealization: Adaptive Integrated Approach for Idealization of Ion Channel Currents (AI2)
Madoka Sato, Masanori Hariyama, Komiya Maki +4
Single-channel electrophysiological recordings provide insights into transmembrane ion permeation and channel gating mechanisms. The first step in the analysis of the recorded curr…
Biological neurons act as generalization filters in reservoir computing
Takuma Sumi, Hideaki Yamamoto, Yuichi Katori +4
Reservoir computing is a machine learning paradigm that transforms the transient dynamics of high-dimensional nonlinear systems for processing time-series data. Although reservoir…
Modular architecture facilitates noise-driven control of synchrony in neuronal networks
Hideaki Yamamoto, F. Paul Spitzner, Taiki Takemuro +9
Brain functions require both segregated processing of information in specialized circuits, as well as integration across circuits to perform high-level information processing. One…
Microfluidic cell engineering on high-density microelectrode arrays for assessing structure-function relationships in living neuronal networks
Yuya Sato, Hideaki Yamamoto, Hideyuki Kato +3
Neuronal networks in dissociated culture combined with cell engineering technology offer a pivotal platform to constructively explore the relationship between structure and functio…
PDMS microfluidic film for in vitro engineering of mesoscale neuronal networks
Taiki Takemuro, Hideaki Yamamoto, Shigeo Sato +1
Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes wh…
Characterization of bulk nanobubbles formed by using a porous alumina film with ordered nanopores
Teng Ma, Yasuo Kimura, Hideaki Yamamoto +3
Gaseous nanobubbles (NBs), with their unique physicochemical properties and promising applications, have become an important research topic. Generation of monodispersed bulk NBs wi…
Optical transport of sub-micron lipid vesicles along an optical nanofibre
Takaaki Yoshino, Daichi Yamaura, Maki Komiya +6
Enhanced manipulation and analysis of bio-particles using light confined in nano-scale dielectric structures has proceeded apace in the last several years. Small mode volumes, alon…
Suppression of hypersynchronous network activity in cultured cortical neurons using an ultrasoft silicone scaffold
Takuma Sumi, Hideaki Yamamoto, Ayumi Hirano-Iwata
The spontaneous activity pattern of cortical neurons in dissociated culture is characterized by burst firing that is highly synchronized among a wide population of cells. The degre…
A Teflon-based system for applying multidirectional voltages to lipid bilayers as a novel platform for membrane proteins
Maki Komiya, Kensaku Kanomata, Ryo Yokota +13
Artificial bilayer lipid membranes (BLMs), along with patch-clamped membranes, are frequently used for functional analyses of membrane proteins. In both methods, the electric prope…