16 citations · 18 across the 5 of their papers we have counts for
8 papers
Automated CFD shape optimization of stator blades for the PediaFlow pediatric ventricular assist device
Mansur Zhussupbekov, Greg W Burgreen, Jeongho Kim +1
PediaFlow is a miniature mixed-flow ventricular assist device for neonates and toddlers. PediaFlow has a fully magnetically levitated rotor which improves biocompatibility, but the…
A continuum model for the unfolding of von Willebrand Factor
Mansur Zhussupbekov, Rodrigo Mendez Rojano, Wei-Tao Wu +2
von Willebrand Factor is a mechano-sensitive protein circulating in blood that mediates platelet adhesion to subendothelial collagen and platelet aggregation at high shear rates. I…
Uncertainty quantification of a thrombosis model considering the clotting assay PFA-100
Rodrigo Méndez Rojano, Mansur Zhussupbekov, James F. Antaki +1
Mathematical models of thrombosis are currently used to study clinical scenarios of pathological thrombus formation. Most of these models involve inherent uncertainties that must b…
Synergistic effect of shear and ADP on platelet growth on ZTA and Ti6Al4V surfaces
Anjana Jayaraman, Junhyuk Kang, Megan A. Jamiolkowski +3
Continuous-flow ventricular assist devices (VADs) have been an increasingly common, life-saving therapy for advanced heart-failure patients, but elevate the risk of thrombosis due…
Multi-scale simulation of thrombus formation at LVAD inlet cannula connection: Importance of Virchow's triad
R. Mendez Rojano, M. Zhussupbekov, J. F. Antaki
As pump thrombosis is reduced in current-generation ventricular assist devices (VAD), adverse events such as bleeding or stroke remain at unacceptable rates. Thrombosis around the…
Influence of shear rate and surface chemistry on thrombus formation in micro-crevice
Mansur Zhussupbekov, Wei-Tao Wu, Megan A. Jamiolkowski +2
Thromboembolic complications remain a central issue in management of patients on mechanical circulatory support. Despite the best practices employed in design and manufacturing of…