activity
20192024
most citedMolten globule-like transition state of protein barnase measured with calorimetric force spectroscopy

42 citations · 106 across the 9 of their papers we have counts for

collaborators

9 papers

q-bio.BM2024

DNA Calorimetric Force Spectroscopy at Single Base Pair Resolution

Paolo Rissone, Marc Rico-Pasto, Steve Smith +1

DNA hybridization is a fundamental reaction with wide-ranging applications in biotechnology. The nearest-neighbor (NN) model provides the most reliable description of the energetic…

cond-mat.stat-mech2023★ 1 cited

Detecting molecular folding from noise measurements

Marc Rico, Felix Ritort

Detecting conformational transitions in molecular systems is key to understanding biological processes. Here, we investigate the force variance in single-molecule pulling experimen…

cond-mat.dis-nn2022★ 10 cited

Experimental test of Sinai's model in DNA unzipping

Cathelijne ter Burg, Paolo Rissone, Marc Rico-Pasto +2

The experimental measurement of correlation functions and critical exponents in disordered systems is key to testing renormalization group (RG) predictions. We mechanically unzip s…

cond-mat.soft2022★ 42 cited

Molten globule-like transition state of protein barnase measured with calorimetric force spectroscopy

Marc Rico-Pasto, Annamaria Zaltron, Sebastian J. Davies +2

Understanding how proteins fold into their native structure is a fundamental problem in biophysics, crucial for protein design. It has been hypothesized that the formation of a mol…

cond-mat.soft2022★ 14 cited

Force-Dependent Folding Kinetics of Single Molecules with Multiple Intermediates and Pathways

Marc Rico-Pasto, Anna Alemany, Felix Ritort

Most single-molecule studies derive the kinetic rates of native, intermediate, and unfolded states from equilibrium hopping experiments. Here, we apply Kramers kinetic diffusive mo…

cond-mat.soft2021★ 7 cited

Force Dependence of Proteins' Transition State Position and the Bell-Evans Model

M. Rico-Pasto, A. Zaltron, F. Ritort

Single-molecule force spectroscopy has opened a new field of research in molecular biophysics and biochemistry. Pulling experiments on individual proteins permit us to monitor conf…

cond-mat.stat-mech2021★ 12 cited

Dissipation reduction and information-to-measurement conversion in DNA pulling experiments with feedback protocols

Marc Rico-Pasto, Regina K. Schmitt, Marco Ribezzi-Crivellari +4

Information-to-energy conversion with feedback measurement stands as one of the most intriguing aspects of the thermodynamics of information in the nanoscale. To date, experiments…

cond-mat.stat-mech2021★ 2 cited

Information-to-work conversion in single molecule experiments: from discrete to continuous feedback

Regina K. Schmitt, Patrick P. Potts, Heiner Linke +4

We theoretically investigate the extractable work in single molecule unfolding-folding experiments with applied feedback. Using a simple two-state model, we obtain a description of…

physics.bio-ph2019★ 18 cited

Force Feedback Effects on Single Molecule Hopping and Pulling Experiments

Marc Rico-Pasto, Isabel Pastor, Felix Ritort

Single-molecule experiments with optical tweezers have become an important tool to study the properties and mechanisms of biological systems, such as cells and nucleic acids. In pa…