From the 1 of 5 linked papers with an AI index.
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Branching-Time Signatures of Growth Regime in Tumor Birth-Death Models
Meng Wang, Zhangchi Weng, Jasmine Foo +1
The paper investigates how the distribution of internal branching times in phylogenetic trees derived from tumor cells reflects different tumor growth regimes, comparing exponentia…
Optimal dosing of anti-cancer treatment under drug-induced plasticity
Einar Bjarki Gunnarsson, Benedikt Vilji Magnússon, Jasmine Foo
While cancer has traditionally been considered a genetic disease, mounting evidence indicates an important role for non-genetic (epigenetic) mechanisms. Common anti-cancer drugs ha…
A statistical framework for detecting therapy-induced resistance from drug screens
Chenyu Wu, Einar Bjarki Gunnarsson, Jasmine Foo +1
Resistance to therapy remains a significant challenge in cancer treatment, often due to the presence of a stem-like cell population that drives tumor recurrence post-treatment. Mor…