3 papers
q-bio.BM2025
Insights into the role of dynamical features in protein complex formation: the case of SARS-CoV-2 spike binding with ACE2
Greta Grassmann, Mattia Miotto, Francesca Alessandrini +4
The functionality of protein-protein complexes is closely tied to the strength of their interactions, making the evaluation of binding affinity a central focus in structural biolog…
q-bio.BM2024
Compact assessment of molecular surface complementarities enhances neural network-aided prediction of key binding residues
Greta Grassmann, Lorenzo Di Rienzo, Giancarlo Ruocco +2
Predicting interactions between biomolecules, such as protein-protein complexes, remains a challenging problem. Despite the many advancements done so far, the performances of docki…
q-bio.QM2024
Zepyros: A webserver to evaluate the shape complementarity of protein-protein interfaces
Mattia Miotto, Lorenzo Di Rienzo, Leonardo Bo' +2
Shape complementarity of molecular surfaces at the interfaces is a well-known characteristic of protein-protein binding regions, and it is critical in influencing the stability of…