2 papers
q-bio.QM2025
Reconstructing Heterogeneous Biomolecules via Hierarchical Gaussian Mixtures and Part Discovery
Shayan Shekarforoush, David B. Lindell, Marcus A. Brubaker +1
Cryo-EM is a transformational paradigm in molecular biology where computational methods are used to infer 3D molecular structure at atomic resolution from extremely noisy 2D electr…
cs.CV2024
CryoSPIN: Improving Ab-Initio Cryo-EM Reconstruction with Semi-Amortized Pose Inference
Shayan Shekarforoush, David B. Lindell, Marcus A. Brubaker +1
Cryo-EM is an increasingly popular method for determining the atomic resolution 3D structure of macromolecular complexes (eg, proteins) from noisy 2D images captured by an electron…