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cond-mat.stat-mech2002
Crucial stages of protein folding through a solvable model: predicting target sites for enzyme-inhibiting drugs
Cristian Micheletti, Fabio Cecconi, Alessandro Flammini +1
An exactly solvable model based on the topology of a protein native state is applied to identify bottlenecks and key-sites for the folding of HIV-1 Protease. The predicted sites ar…
physics.bio-ph2002
Geometry of compact tubes and protein structures
J. R. Banavar, A. Flammini, D. Marenduzzo +2
Proteins form a very important class of polymers. In spite of major advances in the understanding of polymer science, the protein problem has remained largely unsolved. Here, we sh…