3 citations · 3 across the 4 of their papers we have counts for
5 papers
Energetics of Protein Thermodynamic Cooperativity: Contributions of Local and Nonlocal Interactions
Michael Knott, Huseyin Kaya, Hue Sun Chan
The respective roles of local and nonlocal interactions in the thermodynamic cooperativity of proteins are investigated using continuum (off-lattice) native-centric Gō-like models…
Contact Order Dependent Protein Folding Rates: Kinetic Consequences of a Cooperative Interplay Between Favorable Nonlocal Interactions and Local Conformational Preferences
Huseyin Kaya, Hue Sun Chan
Physical mechanisms underlying the empirical correlation between relative contact order (CO) and folding rate among naturally-occurring small single-domain proteins are investigate…
Simple Two-State Protein Folding Kinetics Requires Near-Levinthal Thermodynamic Cooperativity
Huseyin Kaya, Hue Sun Chan
Simple two-state folding kinetics of many small single-domain proteins are characterized by chevron plots with linear folding and unfolding arms consistent with a two-state descrip…
Solvation Effects and Driving Forces for Protein Thermodynamic And Kinetic Cooperativity: How Adequate Is Native-Centric Topological Modeling?
Huseyin Kaya, Hue Sun Chan
What energetic and solvation effects underlie the remarkable two-state thermodynamics and folding/unfolding kinetics of small single-domain proteins? To address this question, we i…
Towards A Consistent Modeling Of Protein Thermodynamic And Kinetic Cooperativity: How Applicable Is The Transition State Picture To Folding and Unfolding?
Huseyin Kaya, Hue Sun Chan
To what extent do general features of folding/unfolding kinetics of small globular proteins follow from their thermodynamic properties? To address this question, we investigate a n…