381 citations · 2.2k across the 24 of their papers we have counts for
24 papers
Analytical Formulation and Field-Theoretic Simulation of Sequence-Specific Phase Separation of Proteinlike Heteropolymers with Short- and Long-Spatial-Range Interactions
Jonas Wessén, Suman Das, Tanmoy Pal +1
A theory for sequence dependent liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) in the study of biomolecular condensates is formulated by extendin…
Field theory description of ion association in re-entrant phase separation of polyampholytes
Jonas Wessén, Tanmoy Pal, Hue Sun Chan
Phase separation of several different overall neutral polyampholyte species (with zero net charge) is studied in solution with two oppositely charged ion species that can form ion-…
Numerical Techniques for Applications of Analytical Theories to Sequence-Dependent Phase Separations of Intrinsically Disordered Proteins
Yi-Hsuan Lin, Jonas Wessén, Tanmoy Pal +2
Biomolecular condensates, physically underpinned to a significant extent by liquid-liquid phase separation (LLPS), are now widely recognized by numerous experimental studies to be…
Assembly of Model Postsynaptic Densities Involves Interactions Auxiliary to Stoichiometric Binding
Yi-Hsuan Lin, Haowei Wu, Bowen Jia +2
The assembly of functional biomolecular condensates often involves liquid-liquid phase separation (LLPS) of proteins with multiple modular domains, which can be folded or conformat…
Small-Angle X-Ray Scattering Signatures of Conformational Heterogeneity and Homogeneity of Disordered Protein Ensembles
Jianhui Song, Jichen Li, Hue Sun Chan
Physically, disordered ensembles of non-homopolymeric polypeptides are expected to be heterogeneous; i.e., they should differ from those homogeneous ensembles of homopolymers that…
A Simple Explicit-Solvent Model of Polyampholyte Phase Behaviors and its Ramifications for Dielectric Effects in Biomolecular Condensates
Jonas Wessén, Tanmoy Pal, Suman Das +2
Biomolecular condensates such as membraneless organelles, underpinned by liquid-liquid phase separation (LLPS), are important for physiological function, with electrostatics -- amo…