2 papers
q-bio.GN2026
Harmonised benchmarking of foundation models for single-cell and spatial transcriptomics reveals context-dependent generalisation
Sally Chen, Roxana Zahedi, Lucy Chhuo +11
Single-cell and spatial foundation models promise transferable biological representations, yet their generality remains largely untested across modalities, biological domains and a…
q-bio.GN2026
Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability
Yuheng Liang, Lucy Chhuo, Ahmadreza Argha +8
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; yet substantial proportion of patients exhibit intrinsic or acquired resistance, making accurate pre-treatment…