2 papers
q-bio.BM2025
Data-driven Discovery of Biophysical T Cell Receptor Co-specificity Rules
Andrew G. T. Pyo, Yuta Nagano, Martina Milighetti +5
The biophysical interactions between the T cell receptor (TCR) and its ligands determine the specificity of the cellular immune response. However, the immense diversity of receptor…
physics.bio-ph2024
Maximum entropy models for patterns of gene expression
Camilla Sarra, Leopoldo Sarra, Luca Di Carlo +4
New experimental methods make it possible to measure the expression levels of many genes, simultaneously, in snapshots from thousands or even millions of individual cells. Current…