66 citations · 150 across the 23 of their papers we have counts for
10 papers · 1 filter
Spike conformation transition in SARS-CoV-2 infection
Liaofu Luo, Yongchun Zuo
A theory on the conformation transition for SARS-CoV-2 spike protein (S) is proposed. The conformation equilibrium between open (up) and closed (down) conformations of receptor bin…
DNA Torsion-based Model of Cell Fate Phase Transitions
Ng Shyh-Chang, Liaofu Luo
All stem cell fate transitions, including the metabolic reprogramming of stem cells and the somatic reprogramming of fibroblasts into pluripotent stem cells, can be understood from…
From Chemically to Physically Induced Pluripotency in Stem Cell
Liaofu Luo
A quantum model on the chemically and physically induced pluripotency in stem cells is proposed. Based on the conformational Hamiltonian and the idea of slow variables (molecular t…
Quantum Theory on Glucose Transport Across Membrane
Liaofu Luo
After a brief review of the protein folding quantum theory and a short discussion on its experimental evidences the mechanism of glucose transport across membrane is studied from t…
Quantum conformational transition in biological macromolecule
LiaoFu Luo
The conformational change of biological macromolecule is investigated from the point of quantum transition. A quantum theory on protein folding is proposed. Compared with other dyn…
A Proposal on Quantum Histone Modification in Gene Expression
Liaofu Luo
A quantum mechanical model on histone modification is proposed. Along with the methyl / acetate or other groups bound to the modified residues the torsion angles of the nearby hist…