1 citations · 2 across the 3 of their papers we have counts for
5 papers
How genome redundancy can promote evolutionary innovation
Domenico Caudo, Mattia Miotto, Giancarlo Ruocco +1
Polyploidy is defined as the existence of more than two complete sets of homologous chromosomes. Despite it being a widespread phenomenon across the tree of life, its role as eithe…
Inheritance Entropy: A Model-Independent Method to Probe the Hereditary Structure of Cell Lineage Trees
Alessandro Allegrezza, Riccardo Beschi, Domenico Caudo +14
Human bone marrow stromal cells (BMSC) include skeletal stem cells with ground-breaking therapeutic potential. However, BMSC colonies have very heterogeneous in vivo behaviour, due…
VertAX: a differentiable vertex model for learning epithelial tissue mechanics
Alessandro Pasqui, Jim Martin Catacora Ocana, Anshuman Sinha +7
Epithelial tissues dynamically reshape through local mechanical interactions among cells, a process well captured by vertex models. Yet their many tunable parameters make inference…
Lineage topology, replication kinetics and cell cycle synchronization reveal regulated growth dynamics in human bone marrow stromal cell colonies
Alessandro Allegrezza, Riccardo Beschi, Domenico Caudo +14
Bone marrow stromal cells (BMSC) -- which include skeletal stem cells -- are a promising tool in regenerative medicine. However, their heterogeneous and unpredictable in vivo behav…
Robust assessment of asymmetric division in colon cancer cells
Domenico Caudo, Chiara Giannattasio, Simone Scalise +6
Asymmetric partition of fate determinants during cell division is a hallmark of cell differentiation. Recent work suggested that such a mechanism is hijacked by cancer cells to inc…