activity
20002016
most citedLethality and centrality in protein networks

5.3k citations · 14.2k across the 12 of their papers we have counts for

collaborators

12 papers

q-bio.QM2016★ 5 cited

Distributed Gradient Descent in Bacterial Food Search

Shashank Singh, Sabrina Rashid, Zhicheng Long +4

Communication and coordination play a major role in the ability of bacterial cells to adapt to ever changing environments and conditions. Recent work has shown that such coordinati…

physics.bio-ph2011★ 1 cited

Stochastic modeling of p53-regulated apoptosis upon radiation damage

Divesh Bhatt, Zoltan Oltvai, Ivet Bahar

We develop and study the evolution of a model of radiation induced apoptosis in cells using stochastic simulations, and identified key protein targets for effective mitigation of r…

q-bio.MN2006★ 23 cited

Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae

Illes J. Farkas, Chuang Wu, Chakra Chennubhotla +2

BACKGROUND. Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carrie…

q-bio.MN2006★ 142 cited

The Activity Reaction Core and Plasticity of Metabolic Networks

E. Almaas, Z. N. Oltvai, A. -L. Barabasi

Understanding the system level adaptive changes taking place in an organism in response to variations in the environment is a key issue of contemporary biology. Current modeling ap…

cond-mat.dis-nn2004★ 346 cited

The topological relationship between the large-scale attributes and local interaction patterns of complex networks

A. Vazquez, R. Dobrin, D. Sergi +3

Recent evidence indicates that the abundance of recurring elementary interaction patterns in complex networks, often called subgraphs or motifs, carry significant information about…

q-bio.GN2003★ 16 cited

Evolutionary conservation of motif constituents within the yeast protein interaction network

S. Wuchty, Z. N. Oltvai, A. -L. Barabasi

Understanding why some cellular components are conserved across species, while others evolve rapidly is a key question of modern biology. Here we demonstrate that in S. cerevisiae…