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q-bio.SC2021
Elementary Intracellular Ca Signals are Initiated by a Transition of Release Channel System from a Metastable State
Guillermo Veron, Victor A. Maltsev, Michael D. Stern +1
Cardiac muscle contraction is initiated by an elementary Ca signal (called Ca spark) which is achieved by collective action of Ca release channels in a cluster. The mechanism of th…
q-bio.SC2017
Computer Algorithms for Automated Detection and Analysis of Local Ca2+ Releases in Spontaneously Beating Cardiac Pacemaker Cells
Alexander V. Maltsev, Sean P. Parsons, Mary S. Kim +5
Local Ca Releases (LCRs) are crucial events involved in cardiac pacemaker cell function. However, specific algorithms for automatic LCR detection and analysis have not been develop…