1.4k citations · 2.1k across the 9 of their papers we have counts for
10 papers
Covariate adjustment in randomised trials: canonical link functions protect against model mis-specification
Ian R. White, Tim P Morris, Elizabeth Williamson
Covariate adjustment has the potential to increase power in the analysis of randomised trials, but mis-specification of the adjustment model could cause error. We explore what erro…
Introducing the treatment hierarchy question in network meta-analysis
Georgia Salanti, Adriani Nikolakopoulou, Orestis Efthimou +3
Background: Comparative effectiveness research using network meta-analysis can present a hierarchy of competing treatments, from the least to most preferable option. However, the r…
The design and statistical aspects of VIETNARMS: a strategic post-licensing trial of multiple oral direct acting antiviral Hepatitis C treatment strategies in Vietnam
L. McCabe, I. R. White, N. V. Vinh Chau +4
Background Achieving hepatitis C elimination is hampered by the costs of treatment and the need to treat hard-to-reach populations. Treatment access could be widened by shortening…
Handling an uncertain control group event risk in non-inferiority trials: non-inferiority frontiers and the power-stabilising transformation
Matteo Quartagno, A. Sarah Walker, Abdel G. Babiker +4
Background. Non-inferiority (NI) trials are increasingly used to evaluate new treatments expected to have secondary advantages over standard of care, but similar efficacy on the pr…
Using simulation studies to evaluate statistical methods
Tim P Morris, Ian R White, Michael J Crowther
Simulation studies are computer experiments that involve creating data by pseudorandom sampling. The key strength of simulation studies is the ability to understand the behaviour o…
A matrix-based method of moments for fitting multivariate network meta-analysis models with multiple outcomes and random inconsistency effects
Dan Jackson, Sylwia Bujkiewicz, Martin Law +2
Random-effects meta-analyses are very commonly used in medical statistics. Recent methodological developments include multivariate (multiple outcomes) and network (multiple treatme…