activity
20172026
most citedBGnet: Accurate and rapid background estimation in single-molecule localization microscopy with deep neural nets

83 citations · 285 across the 7 of their papers we have counts for

collaborators

8 papers

physics.optics2026★ 1 cited

A thermoelastic limit on the focal intensity in Fabry-Pérot cavities

Jeremy J. Axelrod, Lothar Maisenbacher, Ashwin Singh +4

Light in the mode of a Fabry-Pérot cavity heats the mirror surfaces via optical absorption, causing thermoelastic deformation of the mirror substrates, which in turn dictates the s…

physics.optics2024

Crossed laser phase plates for transmission electron microscopy

Petar N. Petrov, Jessie T. Zhang, Jeremy J. Axelrod +2

For decades since the development of phase-contrast optical microscopy, an analogous approach has been sought for maximizing the image contrast of weakly-scattering objects in tran…

q-bio.QM2024★ 1 cited

Modern approaches to improving phase contrast electron microscopy

Jeremy J. Axelrod, Jessie T. Zhang, Petar N. Petrov +2

Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the develo…

physics.ins-det2020★ 44 cited

High-Power Near-Concentric Fabry-Perot Cavity for Phase Contrast Electron Microscopy

Carter Turnbaugh, Jeremy J. Axelrod, Sara L. Campbell +8

Transmission electron microscopy (TEM) of vitrified biological macromolecules (cryo-EM) is limited by the weak phase contrast signal that is available from such samples. Using a ph…

physics.optics2020★ 34 cited

Addressing systematic errors in axial distance measurements in single-emitter localization microscopy

Petar N. Petrov, W. E. Moerner

Nanoscale localization of point emitters is critical to several methods in optical fluorescence microscopy, including single-molecule super-resolution imaging and tracking. While t…

physics.optics2019★ 83 cited

BGnet: Accurate and rapid background estimation in single-molecule localization microscopy with deep neural nets

Leonhard Möckl, Anish R. Roy, Petar N. Petrov +1

Background fluorescence, especially when it exhibits undesired spatial features, is a primary factor for reduced image quality in optical microscopy. Structured background is parti…

eess.IV2019★ 53 cited

Accurate phase retrieval of complex point spread functions with deep residual neural networks

Leonhard MÖckl, Petar N. Petrov, W. E. Moerner

Phase retrieval, i.e. the reconstruction of phase information from intensity information, is a central problem in many optical systems. Here, we demonstrate that a deep residual ne…

physics.optics2017★ 69 cited

Measurement-based estimation of global pupil functions in 3D localization microscopy

Petar N. Petrov, Yoav Shechtman, W. E. Moerner

We report the use of a phase retrieval procedure based on maximum likelihood estimation (MLE) to produce an improved, experimentally calibrated model of a point spread function (PS…