activity
20092023
most citedConsidering discrepancy when calibrating a mechanistic electrophysiology model

60 citations · 204 across the 12 of their papers we have counts for

collaborators

12 papers

math.DS2023★ 5 cited

Scroll Waves and Filaments in excitable Media of higher spatial Dimension

Marie Cloet, Louise Arno, Desmond Kabus +3

Excitable media are ubiquitous in nature, and in such systems the local excitation tends to self-organize in traveling waves, or in rotating spiral-shaped patterns in two or three…

physics.bio-ph2022

Unconventional Collective Resonance as Nonlinear Mechanism of Ectopic Activity in Excitable Media

Alexander S. Teplenin, Nina N. Kudryashova, Rupamanjari Majumder +3

Many physical, chemical and biological processes rely on intrinsic oscillations to employ resonance responses to external stimuli of certain frequency. Such resonance phenomena in…

stat.CO2020★ 60 cited

Considering discrepancy when calibrating a mechanistic electrophysiology model

Chon Lok Lei, Sanmitra Ghosh, Dominic G. Whittaker +14

Uncertainty quantification (UQ) is a vital step in using mathematical models and simulations to take decisions. The field of cardiac simulation has begun to explore and adopt UQ me…

physics.bio-ph2019

Cardiac Mechano-Electrical Dynamical Instability

L. D. Weise, A. V. Panfilov

In a computational study we reveal a novel dynamical instability of excitation waves in the heartmuscle. The instability manifests itself as gradual local increase in the duration…

nlin.PS2019★ 9 cited

A response function framework for the dynamics of meandering or large-core spiral waves and modulated traveling waves

Hans Dierckx, Alexander V. Panfilov, Henri Verschelde +2

In many oscillatory or excitable systems, dynamical patterns emerge which are stationary or periodic up in a moving frame of reference. Examples include traveling waves or spiral w…

q-bio.TO2018★ 35 cited

Dynamical anchoring of distant Arrhythmia Sources by Fibrotic Regions via Restructuring of the Activation Pattern

Nele Vandersickel, Masaya Watanabe, Qian Tao +3

Rotors are functional reentry sources identified in clinically relevant cardiac arrhythmias, such as ventricular and atrial fibrillation. Ablation targeting rotor sites has resulte…

math.GM2018★ 2 cited

Qualitative analysis of differential equations

Alexander V Panfilov

Here I introduce basic methods of qualitative analysis of differential equations used in mathematical biology for people with minimal mathematical background.

physics.bio-ph2017★ 2 cited

The statistical properties of spiral- and scroll-wave turbulence in cardiac tissue

K. V. Rajany, Anupam Gupta, Alexander V. Panfilov +1

Disorganized electrical activity in the heart leads to sudden cardiac death. To what extent can this electrical turbulence be viewed as classical fluid turbulence,which is an impor…

physics.bio-ph2016★ 4 cited

Scroll-wave dynamics in the presence of ionic and conduction inhomogeneities in an anatomically realistic mathematical model for the pig heart

R. Majumder, R Pandit, A. V. Panfilov

Nonlinear waves of the reaction-diffusion (RD) type occur in many biophysical systems, including the heart, where they initiate cardiac contraction. Such waves can form vortices ca…

nlin.PS2014★ 19 cited

Chiral selection and frequency response of spiral waves in reaction-diffusion systems under a chiral electric field

Bing-Wei Li, Mei-Chun Cai, Hong Zhang +2

Chirality is one of the most fundamental properties of many physical, chemical and biological systems. However, the mechanisms underlying the onset and control of chiral symmetry a…

math-ph2013★ 40 cited

Drift Laws for Spiral Waves on Curved Anisotropic Surfaces

Hans Dierckx, Evelien Brisard, Henri Verschelde +1

Rotating spiral waves organize spatial patterns in chemical, physical and biological excitable systems. Factors affecting their dynamics such as spatiotemporal drift are of great i…

nlin.PS2009★ 28 cited

Anomalous drift of spiral waves in heterogeneous excitable media

S. Sridhar, Sitabhra Sinha, Alexander. V. Panfilov

We study the drift of spiral waves in a simple model of heterogeneous excitable medium, having gradients in local excitability or cellular coupling. For the first time, we report t…