50 citations · 133 across the 15 of their papers we have counts for
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The Role of Cytonemes and Diffusive Transport in the Establishment of Morphogen Gradients
Jay A. Stotsky, Hans G. Othmer
Spatial distributions of morphogens provide positional information in developing systems, but how the distributions are established and maintained remains an open problem. Transpor…
A Model for Direction Sensing in Dictyostelium Discoideum: Ras Activity and Symmetry Breaking Driven by a Gbetagamma- Mediated, Galpha2-Ric8 -- Dependent Signal Transduction Network
Yougan Cheng, Hans Othmer
Many eukaryotic cells, including Dictyostelium discoideum (Dicty), neutrophils and other cells of the immune system, can detect and reliably orient themselves in chemoattractant gr…
Computational Analysis of Amoeboid Swimming at Low Reynolds Number
Qixuan Wang, Hans G. Othmer
Recent experimental work has shown that eukaryotic cells can swim in a fluid as well as crawl on a substrate. We investigate the swimming behavior of Dictyostelium discoideum amoeb…
Signal transduction and directional sensing in eukaryotes
Varunyu Khamviwath, Hans G. Othmer
Control of the cytoskeleton and mechanical contacts with the extracellular environment are essential component of motility in eukaryotic cells. In the absence of signals, cells con…
Taxis Equations for Amoeboid Cells
Radek Erban, Hans G. Othmer
The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strateg…