118 citations · 182 across the 15 of their papers we have counts for
19 papers
Whole-skull acoustic transparency from a single time-reversal solve for reciprocity-based transducer placement and aperture optimization in transcranial focused ultrasound
Gianmarco Pinton
Transcranial focused ultrasound is limited by the skull, whose thickness, density and curvature aberrate and attenuate the beam in a position- and target-dependent way, making the…
An Angular Spectrum Method for Nonlinear Propagation in Heterogeneous Tissue with Immersed Sources for Ultrasound
Gianmarco Pinton
A modified angular spectrum method (ASM) is developed for three-dimensional nonlinear acoustic propagation through heterogeneous tissue, targeting transcranial and therapeutic ultr…
An open-source framework for predicting ultrasound neuromodulation: bridging tissue elastomechanics and neuron firing dynamics
Gianmarco Pinton
Transcranial focused ultrasound is a non-invasive neuromodulation modality with millimetre-scale resolution, but its biophysical mechanism of action remains unresolved. Exposure is…
A reduced viscoelastic FDTD formulation for ultrasound-driven shear wave propagation in soft tissue
Gianmarco Pinton
Ultrasound-driven shear wave propagation in soft tissue underlies shear wave elastography (SWE) and emerging elastomechanical hypotheses of ultrasonic neuromodulation, both of whic…
IQ-JEPA: A Joint-Embedding Predictive Architecture with a Hermitian Vision Transformer for Sound Speed and Attenuation Estimation from Ultrasound IQ Data
Masashi Sode, Gianmarco Pinton
The speed of sound in tissue is a prerequisite for well-focused imaging and has diagnostic value, but recovering it from raw pulse-echo channel data is fundamentally a nonlinear in…
Spatially heterogeneous power-law attenuation with multiple relaxation mechanisms for ultrasound modeling
Masashi Sode, Gianmarco Pinton
Objective. The soft tissue attenuation laws have a magnitude and frequency dependence that varies across tissue types and generally follow power laws. An accurate model of ultrasou…
mach: ultrafast ultrasound beamforming
Charles Guan, Alexander P. Rockhill, Masashi Sode +1
Purpose: Volumetric ultrafast ultrasound produces massive datasets with high frame rates, dense reconstruction grids, and large channel counts. Beamforming computational demands li…
Ultrasound Lung Aeration Map via Physics-Aware Neural Operators
Jiayun Wang, Oleksii Ostras, Masashi Sode +5
Lung ultrasound is a growing modality in clinics for diagnosing and monitoring acute and chronic lung diseases due to its low cost and accessibility. Lung ultrasound works by emitt…
Benchmark problems for transcranial ultrasound simulation: Intercomparison of compressional wave models
Jean-Francois Aubry, Oscar Bates, Christian Boehm +19
Computational models of acoustic wave propagation are frequently used in transcranial ultrasound therapy, for example, to calculate the intracranial pressure field or to calculate…
Deconstruction and reconstruction of image-degrading effects in the human abdomen using Fullwave: phase aberration, multiple reverberation, and trailing reverberation
Danai Eleni Soulioti, Francisco Santibanez, Gianmarco Pinton
Ultrasound image degradation in the human body is complex and occurs due to the distortion of the wave as it propagates to and from the target. Here, we establish a simulation base…
A fullwave model of the nonlinear wave equation with multiple relaxations and relaxing perfectly matched layers for high-order numerical finite-difference solutions
Masashi Sode, Gianmarco Pinton
Large-scale acoustic simulations underpin the development of ultrasound imaging and therapy, but modeling nonlinearity, frequency-dependent attenuation, and absorbing boundaries in…
In situ ultrasound imaging of shear shock waves in the porcine brain
Sandhya Chandrasekaran, Francisco Santibanez, Bharat B. Tripathi +2
Using high frame-rate ultrasound and high sensitivity motion tracking, we recently showed that shear waves sent to the ex vivo porcine brain develop into shear shock waves with des…
Super-resolved shear shock focusing in the human head
Bharat B. Tripathi, Sandhya Chandrasekaran, Gianmarco Pinton
Shear shocks, which exist in a completely different regime from compressional shocks, were recently observed in the brain. These low phase speed ( 2 m/s) high Mach number…
Ultrasound imaging of the human body with three dimensional full-wave nonlinear acoustics. Part 1: simulations methods
Gianmarco Pinton
Simulations of three dimensional ultrasound propagation in heterogeneous media are computationally intensive due to the constraints arising from the large size of the domain, which…
Ultrasound imaging with three dimensional full-wave nonlinear acoustic simulations. Part 2: sources of image degradation in intercostal imaging
Gianmarco Pinton
Fullwave simulations are applied to an intercostal imaging scenario to determine the sources of fundamental and harmonic image degradation with respect to aberration and reverberat…
Modeling ultrasound propagation in the moving brain: applications to shear shock waves and traumatic brain injury
Sandhya Chandrasekaran, Bharat B. Tripathi, David Espíndola +1
Traumatic brain injury studies on the living human brain are experimentally infeasible. We present a simulation approach that models ultrasound propagation in the human brain while…
Quantitative sub-resolution blood velocity estimation using ultrasound localization microscopy ex-vivo and in-vivo
David Espindola, Ryan M. DeRuiter, Francisco Santibanez +2
Super-resolution ultrasound imaging relies on the sub-wavelength localization of microbubble contrast agents. By tracking individual microbubbles, the velocity and flow within micr…
Super resolution imaging through the human skull
Danai E. Soulioti, David Espíndola, Paul A. Dayton +1
High resolution transcranial ultrasound imaging in humans has been a persistent challenge for ultrasound due to the imaging degradation effects from aberration and reverberation. T…
Shear shock waves are observed in the brain
David Espindola, Stephen Lee, Gianmarco Pinton
The internal deformation of the brain is far more complex than the rigid motion of the skull. An ultrasound imaging technique that we have developed has a combination of penetratio…