16 citations · 18 across the 3 of their papers we have counts for
3 papers
stat.ME2021★ 2 cited
BaySize: Bayesian Sample Size Planning for Phase I Dose-Finding Trials
Xiaolei Lin, Jiaying Lyu, Shijie Yuan +2
We propose BaySize, a sample size calculator for phase I clinical trials using Bayesian models. BaySize applies the concept of effect size in dose finding, assuming the MTD is defi…
stat.ME2020★ 16 cited
MUCE: Bayesian Hierarchical Modeling for the Design and Analysis of Phase 1b Multiple Expansion Cohort Trials
Jiaying Lyu, Tianjian Zhou, Shijie Yuan +2
We propose a multiple cohort expansion (MUCE) approach as a design or analysis method for phase 1b multiple expansion cohort trials, which are novel first-in-human studies conducte…
stat.ME2017
AAA: Triple-adaptive Bayesian designs for the identification of optimal dose combinations in dual-agent dose-finding trials
Jiaying Lyu, Yuan Ji, Naiqing Zhao +1
We propose a flexible design for the identification of optimal dose combinations in dual-agent dose-finding clinical trials. The design is called AAA, standing for three adaptation…