4 papers
Bayesian modelling of response to therapy and drug-sensitivity in acute lymphoblastic leukemia
Andrea Cremaschi, Wenjian Yang, Maria De Iorio +3
Acute lymphoblastic leukemia (ALL) is a heterogeneous hematologic malignancy involving the abnormal proliferation of immature lymphocytes, accounting for most pediatric cancer case…
Bayesian Inference for Latent Chain Graphs
Deng Lu, Maria De Iorio, Ajay Jasra +1
In this article we consider Bayesian inference for partially observed Andersson-Madigan-Perlman (AMP) Gaussian chain graph (CG) models. Such models are of particular interest in ap…
Discovering Interactions Using Covariate Informed Random Partition Models
Garritt L. Page, Fernando A. Quintana, Gary L. Rosner
Combination chemotherapy treatment regimens created for patients diagnosed with childhood acute lymphoblastic leukemia have had great success in improving cure rates. Unfortunately…
Individualized Treatment Effects with Censored Data via Fully Nonparametric Bayesian Accelerated Failure Time Models
Nicholas C. Henderson, Thomas A. Louis, Gary L. Rosner +1
Individuals often respond differently to identical treatments, and characterizing such variability in treatment response is an important aim in the practice of personalized medicin…