52 citations · 128 across the 5 of their papers we have counts for
5 papers
Structural reduction of chemical reaction networks based on topology
Yuji Hirono, Takashi Okada, Hiroyasu Miyazaki +1
We develop a model-independent reduction method of chemical reaction systems based on the stoichiometry, which determines their network topology. A subnetwork can be eliminated sys…
Structural Bifurcation Analysis in Chemical Reaction Networks
Takashi Okada, Je-Chiang Tsai, Atsushi Mochizuki
In living cells, chemical reactions form a complex network. Complicated dynamics arising from such networks are the origins of biological functions. We propose a novel mathematical…
Ligand-concentration sensitivity of a multi-state receptor
Takashi Okada
Biological sensory systems generally operate out of equilibrium, which often leads to their improved performance. Here, we study the sensitivity of ligand concentration for a gener…
Sensitivity and Network Topology in Chemical Reaction Systems
Takashi Okada, Atsushi Mochizuki
In living cells, biochemical reactions are catalyzed by specific enzymes and connect to one another by sharing substrates and products, forming complex networks. In our previous st…
Law of localization in chemical reaction networks
Takashi Okada, Atsushi Mochizuki
In living cells, chemical reactions are connected by sharing their products and substrates, and form complex networks, e.g. metabolic pathways. Here we developed a theory to predic…