52 citations · 144 across the 7 of their papers we have counts for
7 papers
Non-Fickian single-file pore transport
Spencer Farrell, Andrew D Rutenberg
Single file diffusion (SFD) exhibits anomalously slow collective transport when particles are able to immobilize by binding and unbinding to the one-dimensional channel within whic…
Interpretable machine learning for high-dimensional trajectories of aging health
Spencer Farrell, Arnold Mitnitski, Kenneth Rockwood +1
We have built a computational model for individual aging trajectories of health and survival, which contains physical, functional, and biological variables, and is conditioned on d…
The potential for complex computational models of aging
Spencer Farrell, Garrett Stubbings, Kenneth Rockwood +2
The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting phys…
Anomalously slow transport in single-file diffusion with slow binding kinetics
Spencer G. Farrell, Andrew D. Rutenberg
We computationally study the effects of binding kinetics to the channel wall, leading to transient immobility, on the diffusive transport of particles within narrow channels, that…
Probing the network structure of health deficits in human aging
Spencer G. Farrell, Arnold B. Mitnitski, Olga Theou +2
We confront a network model of human aging and mortality in which nodes represent health attributes that interact within a scale-free network topology, with observational data that…
Unifying ageing and frailty through complex dynamical networks
Andrew D. Rutenberg, Arnold B. Mitnitski, Spencer Farrell +1
To explore the mechanistic relationships between ageing, frailty and mortality, we developed a computational model in which possible health attributes are represented by the nodes…