92 citations · 207 across the 7 of their papers we have counts for
6 papers · 1 filter
Comment on Buss et al., Science 2021: An alternative, empirically-supported adjustment for sero-reversion yields a 10 percentage point lower estimate of the cumulative incidence of SARS-CoV-2 in Manaus by October 2020
Sarah Kadelka, Judith A Bouman, Peter Ashcroft +1
The estimate of the cumulative incidence of SARS-CoV-2 of 76% in Manaus by October 2020 by Buss et al. relies on the assumption of an exponentially-declining probability of sero-re…
COVID-19 infectivity profile correction
Peter Ashcroft, Jana S. Huisman, Sonja Lehtinen +4
The infectivity profile of an individual with COVID-19 is attributed to the paper Temporal dynamics in viral shedding and transmissibility of COVID-19 by He et al., published in Na…
Clonal Dominance and Transplantation Dynamics in Hematopoietic Stem Cell Compartments
Peter Ashcroft, Markus G. Manz, Sebastian Bonhoeffer
Hematopoietic stem cells in mammals are known to reside mostly in the bone marrow, but also transitively passage in small numbers in the blood. Experimental findings have suggested…
Effects of population growth on the success of invading mutants
Peter Ashcroft, Cassandra E. R. Smith, Matthew Garrod +1
Understanding if and how mutants reach fixation in populations is an important question in evolutionary biology. We study the impact of population growth has on the success of muta…
Stochastic tunneling and metastable states during the somatic evolution of cancer
Peter Ashcroft, Franziska Michor, Tobias Galla
Tumors initiate when a population of proliferating cells accumulates a certain number and type of genetic and/or epigenetic alterations. The population dynamics of such sequential…
Fixation in finite populations evolving in fluctuating environments
Peter Ashcroft, Philipp M Altrock, Tobias Galla
The environment in which a population evolves can have a crucial impact on selection. We study evolutionary dynamics in finite populations of fixed size in a changing environment.…