58 citations · 177 across the 41 of their papers we have counts for
10 papers · 1 filter
Estimand frameworks for causal inference in clinical research and regulatory decision making
Miguel A. Hernán, Mats J. Stensrud, Xabier García-Albéniz +2
Causal inference for clinical and regulatory decision making requires a precise definition of the causal estimand, that is, what we want to estimate. Three frameworks are commonly…
Optimal sequential decision-making with initiation regimes
Julien D. Laurendeau, Leora Sarvet, Mats J. Stensrud
Consider an optimal dynamic treatment regime, correctly identified from a large, perfectly executed sequentially randomized experiment. Even when the experimenta…
Causal inference with staggered entries and effects that change over calendar time
Lorenzo Gasparollo, Mats J. Stensrud
Studies with staggered entry, in which individuals enroll at different calendar times, are ubiquitous in medicine and related disciplines. Because these studies usually have a fixe…
On the choice of using raw or demographically-corrected scores
Ignacio Gonzalez-Perez, Mats Julius Stensrud, Marco Piccininni
Demographic corrections are routinely performed in many disciplines, including psychology. Yet, there are ongoing debates about whether these corrections are appropriate and improv…
Causal Inference for All: Marginal Estimands for Outcomes Truncated by Death
Ruixuan Zhao, Mats Stensrud, Linbo Wang
In longitudinal studies, outcomes of interest are often truncated by death, meaning that they are only observed or well-defined conditional on intercurrent events such as survival.…
Trust Me, I'm a Doctor?
Zach Shahn, Mats Stensrud
Clinical trials usually target average treatment effects, but treatment decisions are made for individuals. This tension motivates a common criticism of evidence-based medicine: a…
Sample splitting for valid statistical inference in target trial emulations
Mats Julius Stensrud
\noindent Target trial emulation has improved comparative effectiveness research by making the causal question, assumptions, and analysis plan explicit. However, target trial proto…
On causal inference with marked point process data
Pål Christie Ryalen, Mats Julius Stensrud, Kjetil Røysland
We define dynamic treatment regimes and associated potential outcomes for data described by marked point processes (MPPs). These definitions motivate MPP analogues of the commonly…
Effects conditional on post-treatment events generated by independent mechanisms
Marco Piccininni, Mats J. Stensrud
In both observational studies and randomized trials, post-treatment events such as dropout, nonadherence, and truncation by death occur frequently. In some studies, conditioning on…
Causal Vaccine Effects on Post-infection Outcomes in the Naturally Infected
Allison Codi, Elizabeth Rogawski McQuade, Razieh Nabi +3
Understanding vaccine effects on post-infection outcomes is critical for evaluating the full value proposition of a vaccine. However, defining appropriate causal effects on such ou…