activity
20152024
most citedCell contraction induces long-ranged stress stiffening in the extracellular matrix

316 citations · 612 across the 5 of their papers we have counts for

collaborators

5 papers

physics.optics2024★ 1 cited

Deep and Dynamic Metabolic and Structural Imaging in Living Tissues

Kunzan Liu, Honghao Cao, Kasey Shashaty +13

Label-free imaging through two-photon autofluorescence (2PAF) of NAD(P)H allows for non-destructive and high-resolution visualization of cellular activities in living systems. Howe…

q-bio.CB2018★ 82 cited

Balance of Mechanical Forces Drives Endothelial Gap Formation and May Facilitate Cancer and Immune-Cell Extravasation

Jorge Escribano, Michelle B. Chen, Emad Moeendarbary +5

The formation of gaps in the endothelium is a crucial process underlying both cancer and immune cell extravasation, contributing to the functioning of the immune system during infe…

physics.bio-ph2017★ 316 cited

Cell contraction induces long-ranged stress stiffening in the extracellular matrix

Yu Long Han, Pierre Ronceray, Guoqiang Xu +5

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can signific…

q-bio.TO2017★ 191 cited

Dynamic interplay between tumour, stroma and immune system can drive or prevent tumour progression

R J Seager, Cynthia Hajal, Fabian Spill +2

In the tumour microenvironment, cancer cells directly interact with both the immune system and the stroma. It is firmly established that the immune system, historically believed to…

physics.bio-ph2015★ 22 cited

Effects of 3D Geometries on Cellular Gradient Sensing and Polarization

Fabian Spill, Vivi Andasari, Michael Mak +2

During cell migration, cells become polarized, change their shape, and move in response to various internal and external cues. Cell polarization is defined through the spatio-tempo…