activity
20172026
most citedGeneralised Dice overlap as a deep learning loss function for highly unbalanced segmentations

2.7k citations · 3.9k across the 29 of their papers we have counts for

collaborators

33 papers

cs.CV2026

CenSynCMB: Centre Maps and Physics-Guided Synthesis for Microbleed Detection

Lucas He, Hanyuan Zhang, Krinos Li +7

Cerebral microbleeds (CMBs) are MRI markers of small vessel disease and the microbleed component of amyloid related imaging abnormalities (ARIA-H), but their small size, sparsity,…

cs.CV2026

A Unified Framework for Joint Detection of Lacunes and Enlarged Perivascular Spaces

Lucas He, Krinos Li, Hanyuan Zhang +7

Cerebral small vessel disease (CSVD) markers, specifically enlarged perivascular spaces (EPVS) and lacunae, present a unique challenge in medical image analysis due to their radiol…

cs.CV2026★ 2 cited

Performance uncertainty in medical image analysis: a large-scale investigation of confidence intervals

Pascaline André, Charles Heitz, Evangelia Christodoulou +10

Performance uncertainty quantification is essential for reliable validation and eventual clinical translation of medical imaging artificial intelligence (AI). Confidence intervals…

cs.CV2025★ 1 cited

Medical Imaging AI Competitions Lack Fairness

Annika Reinke, Evangelia Christodoulou, Sthuthi Sadananda +34

Benchmarking competitions are central to the development of artificial intelligence (AI) in medical imaging, defining performance standards and shaping methodological progress. How…

cs.CV2025★ 2 cited

False Promises in Medical Imaging AI? Assessing Validity of Outperformance Claims

Evangelia Christodoulou, Annika Reinke, Pascaline Andrè +23

Performance comparisons are fundamental in medical imaging Artificial Intelligence (AI) research, often driving claims of superiority based on relative improvements in common perfo…

cs.CV2024

Confidence intervals uncovered: Are we ready for real-world medical imaging AI?

Evangelia Christodoulou, Annika Reinke, Rola Houhou +19

Medical imaging is spearheading the AI transformation of healthcare. Performance reporting is key to determine which methods should be translated into clinical practice. Frequently…

cs.CV2023★ 1 cited

Why is the winner the best?

Matthias Eisenmann, Annika Reinke, Vivienn Weru +122

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to in…

cs.CV2023★ 204 cited

Understanding metric-related pitfalls in image analysis validation

Annika Reinke, Minu D. Tizabi, Michael Baumgartner +75

Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation int…

cs.CV2022★ 17 cited

Biomedical image analysis competitions: The state of current participation practice

Matthias Eisenmann, Annika Reinke, Vivienn Weru +352

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known abou…

cs.CV2022★ 6 cited

Where is VALDO? VAscular Lesions Detection and segmentatiOn challenge at MICCAI 2021

Carole H. Sudre, Kimberlin Van Wijnen, Florian Dubost +46

Imaging markers of cerebral small vessel disease provide valuable information on brain health, but their manual assessment is time-consuming and hampered by substantial intra- and…

cs.CV2022★ 469 cited

Metrics reloaded: Recommendations for image analysis validation

Lena Maier-Hein, Annika Reinke, Patrick Godau +71

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen…

physics.med-ph2021★ 1 cited

Evaluation of automated airway morphological quantification for assessing fibrosing lung disease

Ashkan Pakzad, Wing Keung Cheung, Kin Quan +21

Abnormal airway dilatation, termed traction bronchiectasis, is a typical feature of idiopathic pulmonary fibrosis (IPF). Volumetric computed tomography (CT) imaging captures the lo…

stat.AP2021

Diversity of symptom phenotypes in SARS-CoV-2 community infections observed in multiple large datasets

Martyn Fyles, Karina-Doris Vihta, Carole H Sudre +13

Through the use of cutting-edge unsupervised classification techniques from statistics and machine learning, we characterise symptom phenotypes among symptomatic SARS-CoV-2 PCR-pos…

eess.IV2021★ 4 cited

A Decoupled Uncertainty Model for MRI Segmentation Quality Estimation

Richard Shaw, Carole H. Sudre, Sebastien Ourselin +2

Quality control (QC) of MR images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visua…

q-bio.NC2021

Distinguishing Healthy Ageing from Dementia: a Biomechanical Simulation of Brain Atrophy using Deep Networks

Mariana Da Silva, Carole H. Sudre, Kara Garcia +3

Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hype…

eess.IV2021★ 1 cited

Estimating MRI Image Quality via Image Reconstruction Uncertainty

Richard Shaw, Carole H. Sudre, Sebastien Ourselin +1

Quality control (QC) in medical image analysis is time-consuming and laborious, leading to increased interest in automated methods. However, what is deemed suitable quality for alg…

eess.IV2021★ 86 cited

Common Limitations of Image Processing Metrics: A Picture Story

Annika Reinke, Minu D. Tizabi, Carole H. Sudre +90

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation. Performance metrics are…

cs.CV2021

ICAM-reg: Interpretable Classification and Regression with Feature Attribution for Mapping Neurological Phenotypes in Individual Scans

Cher Bass, Mariana da Silva, Carole Sudre +7

An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree…

cs.LG2020★ 4 cited

Biomechanical modelling of brain atrophy through deep learning

Mariana da Silva, Kara Garcia, Carole H. Sudre +3

We present a proof-of-concept, deep learning (DL) based, differentiable biomechanical model of realistic brain deformations. Using prescribed maps of local atrophy and growth as in…

cs.DB2020

Accessible Data Curation and Analytics for International-Scale Citizen Science Datasets

Benjamin Murray, Eric Kerfoot, Mark S. Graham +14

The Covid Symptom Study, a smartphone-based surveillance study on COVID-19 symptoms in the population, is an exemplar of big data citizen science. Over 4.7 million participants and…

eess.IV2020

Test-time Unsupervised Domain Adaptation

Thomas Varsavsky, Mauricio Orbes-Arteaga, Carole H. Sudre +3

Convolutional neural networks trained on publicly available medical imaging datasets (source domain) rarely generalise to different scanners or acquisition protocols (target domain…

cs.CV2020

Hierarchical brain parcellation with uncertainty

Mark S. Graham, Carole H. Sudre, Thomas Varsavsky +4

Many atlases used for brain parcellation are hierarchically organised, progressively dividing the brain into smaller sub-regions. However, state-of-the-art parcellation methods ten…

eess.IV2020★ 38 cited

Learning joint segmentation of tissues and brain lesions from task-specific hetero-modal domain-shifted datasets

Reuben Dorent, Thomas Booth, Wenqi Li +5

Brain tissue segmentation from multimodal MRI is a key building block of many neuroimaging analysis pipelines. Established tissue segmentation approaches have, however, not been de…

cs.LG2020★ 9 cited

ICAM: Interpretable Classification via Disentangled Representations and Feature Attribution Mapping

Cher Bass, Mariana da Silva, Carole Sudre +3

Feature attribution (FA), or the assignment of class-relevance to different locations in an image, is important for many classification problems but is particularly crucial within…