24 citations · 86 across the 13 of their papers we have counts for
17 papers
Ionization detail parameters and cluster dose: A mathematical model for selection of nanodosimetric quantities for use in treatment planning in charged particle radiotherapy
Bruce Faddegon, Eleanor A. Blakely, Lucas Burigo +9
Objective: To propose a mathematical model for applying Ionization Detail (ID), the detailed spatial distribution of ionization along a particle track, to proton and ion beam radio…
A Prototype Scintillator Real-Time Beam Monitor for Ultra-high Dose Rate Radiotherapy
Daniel S. Levin, Peter S. Friedman, Claudio Ferretti +5
FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in…
Repair kinetics of DSB-foci induced by proton and helium ion microbeams of different energies
Ana Belchior, João F. Canhoto, Ulrich Giesen +3
In this work, the induction and repair of radiation-induced 53BP1 foci were studied in human umbilical vein endothelial cells irradiated at the PTB microbeam with protons and α-par…
A stopping criterion for iterative proton CT image reconstruction based on correlated noise properties
Ethan A. DeJongh, Alexander A. Pryanichnikov, Don F. DeJongh +1
Background: Whereas filtered back projection algorithms for voxel-based CT image reconstruction have noise properties defined by the filter, iterative algorithms must stop at some…
A proton simulator for testing implementations of proton CT reconstruction algorithms on GPGPU clusters
Micah Witt, Blake Schultze, Reinhard Schulte +2
Proton computed tomography (pCT) is an image modality that will improve treatment planning for patients receiving proton radiation therapy compared with the current treatment techn…
Developments in Mathematical Algorithms and Computational Tools for Proton CT and Particle Therapy Treatment Planning
Yair Censor, Keith E. Schubert, Reinhard W. Schulte
We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated parti…
A Comparison of Proton Stopping Power Measured with Proton CT and x-ray CT in Fresh Post-Mortem Porcine Structures
Don F. DeJongh, Ethan A. DeJongh, Victor Rykalin +13
Purpose: Currently, calculations of proton range in proton therapy patients are based on a conversion of CT Hounsfield Units of patient tissues into proton relative stopping power.…
Derivative-free superiorization with component-wise perturbations
Yair Censor, Howard Heaton, Reinhard Schulte
Superiorization reduces, not necessarily minimizes, the value of a target function while seeking constraints-compatibility. This is done by taking a solely feasibility-seeking algo…
An Improved Method of Total Variation Superiorization Applied to Reconstruction in Proton Computed Tomography
Blake Schultze, Yair Censor, Paniz Karbasi +2
Previous work showed that total variation superiorization (TVS) improves reconstructed image quality in proton computed tomography (pCT). The structure of the TVS algorithm has evo…
A Highly Accelerated Parallel Multi-GPU based Reconstruction Algorithm for Generating Accurate Relative Stopping Powers
Paniz Karbasi, Ritchie Cai, Blake Schultze +11
Low-dose Proton Computed Tomography (pCT) is an evolving imaging modality that is used in proton therapy planning which addresses the range uncertainty problem. The goal of pCT is…
A Real-time Image Reconstruction System for Particle Treatment Planning Using Proton Computed Tomography (pCT)
Caesar E. Ordoñez, Nicholas Karonis, Kirk Duffin +4
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared t…
Results from a Prototype Proton-CT Head Scanner
R. P. Johnson, V. A. Bashkirov, G. Coutrakon +8
We are exploring low-dose proton radiography and computed tomography (pCT) as techniques to improve the accuracy of proton treatment planning and to provide artifact-free images fo…
A Variable-Energy CW Compact Accelerator for Ion Cancer Therapy
C. Johnstone, J. Taylor, R. Edgecock +1
This paper reports on the conclusions of a 2013 Joint DOE/NCI Workshop, and translates clinical accelerator facility requirements into accelerator and beam-delivery technical speci…
Sparsity constrained split feasibility for dose-volume constraints in inverse planning of intensity-modulated photon or proton therapy
S. Penfold, R. Zalas, M. Casiraghi +3
A split feasibility formulation for the inverse problem of intensity-modulated radiation therapy (IMRT) treatment planning with dose-volume constraints (DVCs) included in the plann…
Performance of Hull-Detection Algorithms For Proton Computed Tomography Reconstruction
Blake Schultze, Micah Witt, Yair Censor +2
Proton computed tomography (pCT) is a novel imaging modality developed for patients receiving proton radiation therapy. The purpose of this work was to investigate hull-detection a…
Projected Subgradient Minimization versus Superiorization
Yair Censor, Ran Davidi, Gabor T. Herman +2
The projected subgradient method for constrained minimization repeatedly interlaces subgradient steps for the objective function with projections onto the feasible region, which is…
Mapping the Sensitive Volume of an Ion-Counting Nanodosimeter
Reinhard Schulte, Vladimir Bashkirov, Sergei Shchemelinin +5
We present two methods of independently mapping the dimensions of the sensitive volume in an ion-counting nanodosimeter. The first method is based on a calculational approach simul…