661 citations · 1.4k across the 22 of their papers we have counts for
22 papers
Correlation between sequence hydrophobicity and surface-exposure pattern of database proteins
Susanne Moelbert, Eldon Emberly, Chao Tang
Hydrophobicity is thought to be one of the primary forces driving the folding of proteins. On average, hydrophobic residues occur preferentially in the core, whereas polar residues…
Flexibility of beta-sheets: Principal-component analysis of database protein structures
Eldon G. Emberly, Ranjan Mukhopadhyay, Chao Tang +1
Protein folds are built primarily from the packing together of two types of structures: alpha-helices and beta-sheets. Neither structure is rigid, and the flexibility of helices an…
Designability and Thermal Stability of Protein Structures
Ned Wingreen, Hao Li, Chao Tang
Only about 1,000 qualitatively different protein folds are believed to exist in nature. Here, we review theoretical studies which suggest that some folds are intrinsically more des…
Origin of Scaling Behavior of Protein Packing Density: A Sequential Monte Carlo Study of Compact Long Chain Polymers
Jinfeng Zhang, Rong Chen, Chao Tang +1
Single domain proteins are thought to be tightly packed. The introduction of voids by mutations is often regarded as destabilizing. In this study we show that packing density for s…
Flexibility of -helices: Results of a statistical analysis of database protein structures
Eldon G. Emberly, Ranjan Mukhopadhyay, Ned S. Wingreen +1
-helices stand out as common and relatively invariant secondary structural elements of proteins. However, -helices are not rigid bodies and their deformations can be signific…
Statistical mechanics of RNA folding: importance of alphabet size
Ranjan Mukhopadhyay, Eldon Emberly, Chao Tang +1
We construct a minimalist model of RNA secondary-structure formation and use it to study the mapping from sequence to structure. There are strong, qualitative differences between t…