16 citations · 49 across the 38 of their papers we have counts for
9 papers · 1 filter
Integrating state-sequence analysis to uncover dynamic drug-utilization patterns to profile heart failure patients
Nicole Fontana, Laura Savaré, Francesca Ieva
Globally, the incidence of heart failure is increasing, and its principal treatment involves drug therapy. However, widespread non-adherence to therapies is prevalent among heart f…
Estimation of Dynamic Origin-Destination Matrices in a Railway Transportation Network integrating Ticket Sales and Passenger Count Data
Greta Galliani, Piercesare Secchi, Francesca Ieva
Accurately estimating Origin-Destination (OD) matrices is a topic of increasing interest for efficient transportation network management and sustainable urban planning. Traditional…
Joint modelling of recurrent and terminal events with discretely-distributed non-parametric frailty: application on re-hospitalizations and death in heart failure patients
Chiara Masci, Marta Spreafico, Francesca Ieva
In the context of clinical and biomedical studies, joint frailty models have been developed to study the joint temporal evolution of recurrent and terminal events, capturing both t…
Dynamic treatment effect phenotyping through functional survival analysis
Caterina Gregorio, Giovanni Baj, Giulia Barbati +1
In recent years, research interest in personalised treatments has been growing. However, treatment effect heterogeneity and possibly time-varying treatment effects are still often…
Scaling Survival Analysis in Healthcare with Federated Survival Forests: A Comparative Study on Heart Failure and Breast Cancer Genomics
Alberto Archetti, Francesca Ieva, Matteo Matteucci
Survival analysis is a fundamental tool in medicine, modeling the time until an event of interest occurs in a population. However, in real-world applications, survival data are oft…
Causal effect of chemotherapy received dose intensity on survival outcome: a retrospective study in osteosarcoma
Marta Spreafico, Francesca Ieva, Marta Fiocco
This study aims to analyse the effects of reducing Received Dose Intensity (RDI) in chemotherapy treatment for osteosarcoma patients on their survival by using a novel approach. In…
A latent class approach to assess the effects of dynamic adherence to polytherapy in heart failure patients
Nicole Fontana, Laura Savaré, Emanuele Di Angelantonio +1
Heart failure (HF) treatment relies heavily on pharmacotherapy, particularly combining multiple therapies as recommended by clinical guidelines. However, non-adherence to prescribe…
Clustering Hierarchies via a Semi-Parametric Generalized Linear Mixed Model: a statistical significance-based approach
Alessandra Ragni, Chiara Masci, Francesca Ieva +1
We introduce a novel statistical significance-based approach for clustering hierarchical data using semi-parametric linear mixed-effects models designed for responses with laws in…
An Evaluation of Researchers' Migration Patterns in Europe using Digital Trace Data
Jacopo Ghirri, Marta Mastropietro, Simone Vantini +2
The comprehension of the mechanisms behind the mobility of skilled workers is of paramount importance for policy making. The lacking nature of official measurements motivates the u…