16 citations · 21 across the 25 of their papers we have counts for
11 papers · 1 filter
Enhancing comorbidity network inference with risk-enriched health trajectories embedding
Nicole Fontana, Alessia Mapelli, Emanuele Di Angelantonio +1
Multimorbidity poses a growing challenge for individual health, reducing quality of life and increasing treatment burden, resulting in a multiplicative impact on healthcare system…
Prior-informed conditional Gaussian graphical models: an application to protein interaction network reconstruction
Alessia Mapelli, Michela Carlotta Massi, Gianmauro Cuccuru +2
Protein-protein interaction (PPI) networks, estimated from high-throughput omics data, foster biomarker discovery and precision medicine. Gaussian graphical models (GGMs) offer a p…
Hidden multistate models to study multimorbidity trajectories
Valentina Manzoni, Francesca Ieva, Amaia Calderón-Larrañaga +2
Multimorbidity in older adults is common, heterogeneous, and highly dynamic, and it is strongly associated with disability and increased healthcare utilization. However, existing a…
Multi-state Modeling of Delay Evolution in Suburban Rail Transports
Stefania Colombo, Alfredo Gimenez Zapiola, Francesca Ieva +1
Train delays are a persistent issue in railway systems, particularly in suburban networks where operational complexity is heightened by frequent services and high passenger volumes…
Unraveling time-varying causal effects of multiple exposures: integrating Functional Data Analysis with Multivariable Mendelian Randomization
Nicole Fontana, Francesca Ieva, Luisa Zuccolo +2
Mendelian Randomization is a widely used instrumental variable method for assessing causal effects of lifelong exposures on health outcomes. Many exposures, however, have causal ef…
Three Distributional Approaches for PM10 Assessment in Northern Italy
Marco F. De Sanctis, Andrea Gilardi, Giacomo Milan +3
We propose three spatial methods for estimating the full probability distribution of PM10 concentrations, with the ultimate goal of assessing air quality in Northern Italy. Moving…