activity
20172023
most citedMembraneless organelles formed by liquid-liquid phase separation increase bacterial fitness

142 citations · 162 across the 5 of their papers we have counts for

collaborators

6 papers

cond-mat.soft2023★ 1 cited

Predicting Rubisco:Linker Condensation from Titration in the Dilute Phase

Alex Payne-Dwyer, Gaurav Kumar, James Barrett +6

The condensation of Rubisco holoenzymes and linker proteins into 'pyrenoids', a crucial super-charger of photosynthesis in algae, is qualitatively understood in terms of 'sticker-a…

cond-mat.soft2021★ 11 cited

Theoretical rheo-physics of silk: Intermolecular associations reduce the critical specific work for flow-induced crystallisation

Charley Schaefer, Tom C. B. McLeish

Silk is a semi-dilute solution of randomly coiled associating polypeptide chains that crystallise following the stretch-induced disruption, in the strong extensional flow of extrus…

q-bio.BM2021★ 142 cited

Membraneless organelles formed by liquid-liquid phase separation increase bacterial fitness

Xin Jin, Ji-Eun Lee, Charley Schaefer +10

Liquid-liquid phase separation is emerging as a crucial phenomenon in several fundamental cell processes. A range of eukaryotic systems exhibit liquid condensates. However, their f…

cond-mat.soft2020★ 5 cited

Power-Law Stretching of Associating Polymers in Steady-State Extensional Flow

Charley Schaefer, Tom C. B. McLeish

We present a tube model for the Brownian dynamics of associating polymers in extensional flow. In linear response, the model confirms the analytical predictions for the sticky diff…

cond-mat.soft2019

Morphology Formation in Binary Mixtures upon Gradual Destabilisation

Charley Schaefer, Stefan Paquay, Tom C. B. McLeish

Spontaneous liquid-liquid phase separation is commonly understood in terms of phenomenological mean-field theories. These theories correctly predict the structural features of the…

physics.chem-ph2017★ 3 cited

Structuring of fluid adlayers upon ongoing unimolecular adsorption

Charley Schaefer

Fluids with spatial density variations of single or mixed molecules play a key role in biophysics, soft matter and materials science. The fluid structures usually form via spinodal…