activity
20112017
most citedRelationships between ligand binding sites, protein architecture and correlated paths of energy and conformational fluctuations

16 citations · 16 across the 7 of their papers we have counts for

collaborators

7 papers

q-bio.BM2017

Entropy Transfer and Dynamics of Allostery in Proteins

Aysima Hacisuleyman, Burak Erman

Allostery is an intrinsic spatiotemporal property of all proteins, resulting from long range correlations in the order of several nanometers and time scales of nanoseconds. Informa…

q-bio.BM2015

Three Universal Distribution Functions for Native Proteins with Harmonic Interactions

Burak Erman

We used statistical thermodynamics of conformational fluctuations and the elements of algebraic graph theory together with data from 2000 protein crystal structures, and showed tha…

q-bio.BM2015

Effects of ligand binding upon flexibility of proteins

Burak Erman

Binding of a ligand on a protein changes the flexibility of certain parts of the protein, which directly affects its function. These changes are not the same at each point, some pa…

q-bio.BM2014

Fractal Structure of Shortest Interaction Paths in Native Proteins and Determination of Residues on a Given Shortest Path

Burak Erman

Fractal structure of shortest paths depends strongly on interresidue interaction cutoff distance. The dimensionality of shortest paths is calculated as a function of interaction cu…

q-bio.QM2013

Mode-coupling points to functionally important residues in Myosin II

Onur Varol, Deniz Yuret, Burak Erman +1

Relevance of mode coupling to energy/information transfer during protein function, particularly in the context of allosteric interactions is widely accepted. However, existing evid…

q-bio.BM2011

The effect of point mutations on energy conduction pathways in proteins

Nazan B. Walpoth, Burak Erman

Energetically responsive residues of the 173 amino acid N-terminal domain of the cardiac Ryanodine receptor RyR2 are identified by a simple elastic net model. Residues that respond…

physics.bio-ph2011★ 16 cited

Relationships between ligand binding sites, protein architecture and correlated paths of energy and conformational fluctuations

Burak Erman

Statistical thermodynamics basis of energy and residue position fluctuations is explained for native proteins. The protein and its surroundings are treated as a canonical system wi…