165 citations · 165 across the 2 of their papers we have counts for
2 papers
physics.bio-ph2017
Proton network flexibility enables robustness and large electric fields in the ketosteroid isomerase active site
Lu Wang, Stephen D. Fried, Thomas E. Markland
Hydrogen bond networks play vital roles in biological functions ranging from protein folding to enzyme catalysis. Here we combine electronic structure calculations and ab initio pa…
physics.chem-ph2015★ 165 cited
Quantum delocalization of protons in the hydrogen bond network of an enzyme active site
Lu Wang, Stephen D. Fried, Steven G. Boxer +1
Enzymes utilize protein architectures to create highly specialized structural motifs that can greatly enhance the rates of complex chemical transformations. Here we use experiments…